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Janaillac M, Labarinas S, Pfister RE, et al. Accuracy of Transcutaneous Carbon Dioxide Measurement in Premature Infants. Crit Care Res Pract. 2016;2016:8041967doi: 10.1155/2016/8041967.
Janaillac, M., Labarinas, S., Pfister, R. E., & Karam, O. (2016). Accuracy of Transcutaneous Carbon Dioxide Measurement in Premature Infants. Critical care research and practice, 20168041967. https://doi.org/10.1155/2016/8041967
Janaillac, Marie, et al. "Accuracy of Transcutaneous Carbon Dioxide Measurement in Premature Infants." Critical care research and practice vol. 2016 (2016): 8041967. doi: https://doi.org/10.1155/2016/8041967
Janaillac M, Labarinas S, Pfister RE, Karam O. Accuracy of Transcutaneous Carbon Dioxide Measurement in Premature Infants. Crit Care Res Pract. 2016;2016:8041967. doi: 10.1155/2016/8041967. Epub 2016 Jun 08. PMID: 27375901; PMCID: PMC4916268.
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Crit Care Res Pract. 2016;2016:8041967. doi: 10.1155/2016/8041967. Epub 2016 Jun 08.

Accuracy of Transcutaneous Carbon Dioxide Measurement in Premature Infants.

Critical care research and practice

Marie Janaillac, Sonia Labarinas, Riccardo E Pfister, Oliver Karam

Affiliations

  1. Neonatal and Pediatric Intensive Care Unit, Geneva University Hospital, Rue Willy Donzé 6, 1250 Geneva, Switzerland.

PMID: 27375901 PMCID: PMC4916268 DOI: 10.1155/2016/8041967

Abstract

Background. In premature infants, maintaining blood partial pressure of carbon dioxide (pCO2) value within a narrow range is important to avoid cerebral lesions. The aim of this study was to assess the accuracy of a noninvasive transcutaneous method (TcpCO2), compared to blood partial pressure of carbon dioxide (pCO2). Methods. Retrospective observational study in a tertiary neonatal intensive care unit. We analyzed the correlation between blood pCO2 and transcutaneous values and the accuracy between the trends of blood pCO2 and TcpCO2 in all consecutive premature infants born at <33 weeks' gestational age. Results. 248 infants were included (median gestational age: 29 + 5 weeks and median birth weight: 1250 g), providing 1365 pairs of TcpCO2 and blood pCO2 values. Pearson's R correlation between these values was 0.58. The mean bias was -0.93 kPa with a 95% confidence limit of agreement of -4.05 to +2.16 kPa. Correlation between the trends of TcpCO2 and blood pCO2 values was good in only 39.6%. Conclusions. In premature infants, TcpCO2 was poorly correlated to blood pCO2, with a wide limit of agreement. Furthermore, concordance between trends was equally low. We warn about clinical decision-making on TcpCO2 alone when used as continuous monitoring.

References

  1. Intensive Care Med. 2009 Nov;35(11):1942-9 - PubMed
  2. Pediatrics. 2007 Feb;119(2):299-305 - PubMed
  3. Paediatr Anaesth. 2009 May;19(5):434-44 - PubMed
  4. Crit Care Med. 2002 May;30(5):1024-7 - PubMed
  5. Pediatrics. 2005 May;115(5):1299-306 - PubMed
  6. Respir Physiol Neurobiol. 2007 Mar 15;155(3):268-79 - PubMed
  7. Adv Exp Med Biol. 1987;220:115-20 - PubMed
  8. Arch Dis Child Fetal Neonatal Ed. 2005 Nov;90(6):F523-6 - PubMed
  9. Chest. 1991 May;99(5):1211-5 - PubMed
  10. Lancet. 1995 Oct 21;346(8982):1085-7 - PubMed
  11. Scand J Clin Lab Invest. 2011 Nov;71(7):548-52 - PubMed
  12. J Perinatol. 2005 Jan;25(1):26-9 - PubMed
  13. Cochrane Database Syst Rev. 2001;(2):CD002061 - PubMed
  14. J Biopharm Stat. 2007;17(4):571-82 - PubMed
  15. Stud Health Technol Inform. 2009;150:490-4 - PubMed
  16. Pediatrics. 1988 May;81(5):684-7 - PubMed
  17. Crit Care Med. 1989 Jun;17(6):556-9 - PubMed
  18. Arch Dis Child. 2007 Mar;92(3):261-5 - PubMed
  19. Arch Dis Child. 2004 Feb;89(2):176-80 - PubMed
  20. Arch Dis Child Fetal Neonatal Ed. 2006 Jul;91(4):F295-8 - PubMed

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