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J Clin Diagn Res. 2016 May;10(5):OD31-2. doi: 10.7860/JCDR/2016/18762.7826. Epub 2016 May 01.

Synthetic Cannabinoid Induced acute Tubulointerstitial Nephritis and Uveitis Syndrome: A Case Report and Review of Literature.

Journal of clinical and diagnostic research : JCDR

Ayse Sinangil, Vedat Celik, Alev Kockar, Tevfik Ecder

Affiliations

  1. Nephrology Specialist Vedat Celik, Division of Nephrology, Department of Internal Medicine, Istanbul Bilim University , Istanbul-Turkey .
  2. Nephrology Specialist Alev Kockar, Division of Nephrology, Department of Internal Medicine, Istanbul Bilim University , Istanbul-Turkey.
  3. Ophtalmotology Specialist Tevfik Ecder, Department of Ophtalmotology, Istanbul Bilim University , Istanbul-Turkey .
  4. Nephrology Professor Division of Nephrology, Department of Internal Medicine, Istanbul Bilim University , Istanbul-Turkey .

PMID: 27437289 PMCID: PMC4948465 DOI: 10.7860/JCDR/2016/18762.7826

Abstract

Tubulointerstitial Nephritis with Uveitis (TINU) syndrome is a rarely seen syndrome. The interstitial nephritis may be with the concurrent uveitis and can also develop before or after uveitis. The syndrome can resolve after elimination of the culprit destructive factors, such as drugs, toxins and immune reaction. Synthetic cannabinoids have emerged as drugs of abuse with increasing popularity among young adults. Recent literature has documented reports of acute kidney injury in association with the use of synthetic cannabinoids; however, there is no report of TINU syndrome development secondary to using of synthetic cannabinoids. Herein, we report a 42-year-old male with TINU syndrome associated with smoking synthetic cannabinoid.

Keywords: Anterior uveitis; Bonsai; Drug abuse; Nephrotoxicity

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