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Colak S, Erdogan MO, Senel A, et al. A Rare Case in the Emergency Department: Holmes-Adie Syndrome. Turk J Emerg Med. 2016;15(1):40-2doi: 10.5505/1304.7361.2015.59144.
Colak, S., Erdogan, M. O., Senel, A., Kibici, O., Karaboga, T., Afacan, M. A., & Akdemir, H. U. (2015). A Rare Case in the Emergency Department: Holmes-Adie Syndrome. Turkish journal of emergency medicine, 15(1), 40-2. https://doi.org/10.5505/1304.7361.2015.59144
Colak, Sahin, et al. "A Rare Case in the Emergency Department: Holmes-Adie Syndrome." Turkish journal of emergency medicine vol. 15,1 (2015): 40-2. doi: https://doi.org/10.5505/1304.7361.2015.59144
Colak S, Erdogan MO, Senel A, Kibici O, Karaboga T, Afacan MA, Akdemir HU. A Rare Case in the Emergency Department: Holmes-Adie Syndrome. Turk J Emerg Med. 2016 Mar 02;15(1):40-2. doi: 10.5505/1304.7361.2015.59144. eCollection 2015 Mar. PMID: 27437522; PMCID: PMC4909970.
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Turk J Emerg Med. 2016 Mar 02;15(1):40-2. doi: 10.5505/1304.7361.2015.59144. eCollection 2015 Mar.

A Rare Case in the Emergency Department: Holmes-Adie Syndrome.

Turkish journal of emergency medicine

Sahin Colak, Mehmet Ozgur Erdogan, Ahmet Senel, Ozge Kibici, Turker Karaboga, Mustafa Ahmet Afacan, Hizir Ufuk Akdemir

Affiliations

  1. Department of Emergency Medicine, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey.

PMID: 27437522 PMCID: PMC4909970 DOI: 10.5505/1304.7361.2015.59144

Abstract

Holmes-Adie syndrome (HAS) is a rare syndrome characterized by tonic pupil and the absence of deep tendon reflexes. HAS was first described in 1931 and is usually idiopathic, with incidences reported to be 4-7 per 100,000. Although tonic pupil is usually unilateral, it can also be bilateral. Enlarged and irregular pupil is usually noticed by the patient. Light reflex is weak or unresponsive. Another characteristic of HAS is the absence of deep tendon reflexes, and unilateral involvement is more common. This case report emphasizes that HAS should be considered in the differential diagnosis of patients presenting to the emergency department with anisocoria, and the dilute pilocarpine test can be used in diagnosis.

Keywords: Emergency department; Holmes-Adie syndrome; pilocarpine

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