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Oliveira M, Patinha F, Marinho A. Eosinophilic fasciitis after parasite infection. Reumatologia. 2016;54(1):38-41doi: 10.5114/reum.2016.58761.
Oliveira, M., Patinha, F., & Marinho, A. (2016). Eosinophilic fasciitis after parasite infection. Reumatologia, 54(1), 38-41. https://doi.org/10.5114/reum.2016.58761
Oliveira, Marta, et al. "Eosinophilic fasciitis after parasite infection." Reumatologia vol. 54,1 (2016): 38-41. doi: https://doi.org/10.5114/reum.2016.58761
Oliveira M, Patinha F, Marinho A. Eosinophilic fasciitis after parasite infection. Reumatologia. 2016;54(1):38-41. doi: 10.5114/reum.2016.58761. Epub 2016 Mar 24. PMID: 27407276; PMCID: PMC4847322.
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Reumatologia. 2016;54(1):38-41. doi: 10.5114/reum.2016.58761. Epub 2016 Mar 24.

Eosinophilic fasciitis after parasite infection.

Reumatologia

Marta Oliveira, Fabia Patinha, Antonio Marinho

Affiliations

  1. Centro Hospitalar Baixo Vouga, Aveiro, Portugal.

PMID: 27407276 PMCID: PMC4847322 DOI: 10.5114/reum.2016.58761

Abstract

Eosinophilic fasciitis is a systemic inflammatory disease characterized by symmetrical swelling and skin induration of the distal portions of the arms and/or legs, evolving into a scleroderma-like appearance, accompanied by peripheral blood eosinophilia. It is a rare disease with a poorly understood etiology. Corticosteroid treatment remains the standard therapy, either taken alone or in association with an immunosuppressive drug. This paper presents a case of a male patient with palpebral edema and marked eosinophilia, diagnosed with intestinal parasitic infection in October 2006. He was treated with an antiparasitic drug, but both the swelling and the analytical changes remained. This was followed by a skin and muscle biopsy, which turned out to be compatible with eosinophilic fasciitis. There was progressive worsening of the clinical state, with stiffness of the abdominal wall and elevated inflammatory parameters, and the patient was referred to the Immunology Department, medicated with corticosteroids and methotrexate. Over the years there were therapeutic adjustments and other causes were excluded. Currently the patient continues to be monitored, and there is no evidence of active disease. The case described in this article is interesting because of the diagnosis of eosinophilic fasciitis probably associated/coexisting with a parasite infection. This case report differs from others in that there is an uncommon cause associated with the onset of the disease, instead of the common causes such as trauma, medication, non-parasitic infections or cancer.

Keywords: allergy; antirheumatic agents; eosinophilic fasciitis; immunology; rheumatology

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