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Data Brief. 2016 Mar 24;7:981-9. doi: 10.1016/j.dib.2016.03.064. eCollection 2016 Jun.

X-ray diffraction and NMR data for the study of the location of idebenone and idebenol in model membranes.

Data in brief

Victoria Gómez-Murcia, Alejandro Torrecillas, Ana M deGodos, Senena Corbalán-García, Juan C Gómez-Fernández

Affiliations

  1. Departamento de Bioquímica y Biología Molecular A, Universidad de Murcia, IMIB-Arrixaca, Campus of International Excellence "Campus Mare Nostrum", Murcia, Spain.

PMID: 27408910 PMCID: PMC4927974 DOI: 10.1016/j.dib.2016.03.064

Abstract

Here we present some of our data about the interaction of idebenone and idebenol with dipalmitoyl-phosphatidylcholine (DPPC). In particular, we include data of small angle X-ray diffraction (SAXD) and wide angle X-ray diffraction experiments, obtention of electronic profiles of the membranes, (2)H-NMR and (31)P-NMR, as part of the research article: "Both idebenone and idebenol are localized near the lipid-water interface of the membrane and increase its fluidity" (Gomez-Murcia et al., 2016) [1]. These data were obtained from model membranes that included different proportions of idebenone and idebenol, at temperatures both above and below of the gel to fluid phase. The X-ray experiments were carried out by using a modified Kratky compact camera (MBraun-Graz-Optical Systems, Graz Austria), incorporating two coupled linear position sensitive detectors. The NMR data were collected from a a Bruker Avance 600 instrument.

Keywords: 2H NMR; 31P NMR; Small angle X-ray diffraction; Wide angle X-ray diffraction

References

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