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Adv Funct Mater. 2016 Jan 13;26(2):267-276. doi: 10.1002/adfm.201503453. Epub 2015 Dec 02.

Tumor-Targeted Multimodal Optical Imaging with Versatile Cadmium-Free Quantum Dots.

Advanced functional materials

Xiangyou Liu, Gary B Braun, Haizheng Zhong, David J Hall, Wenlong Han, Mingde Qin, Chuanzhen Zhao, Meina Wang, Zhi-Gang She, Chuanbao Cao, Michael J Sailor, William B Stallcup, Erkki Ruoslahti, Kazuki N Sugahara

Affiliations

  1. Cancer Research Center, Sanford Burnham Prebys, Medical Discovery Institute, La Jolla, CA 92037, USA.
  2. Beijing Key Laboratory of Nanophotonics and Ultrafine Optoelectronic Systems, School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081, P. R. China.
  3. Moores Cancer Center, Department of Radiology, University of California, San Diego, La Jolla, CA 92093, USA.
  4. Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA.
  5. Research Center of Materials Science, Beijing Institute of Technology, Beijing 100081, P. R. China.

PMID: 27441036 PMCID: PMC4948596 DOI: 10.1002/adfm.201503453

Abstract

The rapid development of fluorescence imaging technologies requires concurrent improvements in the performance of fluorescent probes. Quantum dots have been extensively used as an imaging probe in various research areas because of their inherent advantages based on unique optical and electronic properties. However, their clinical translation has been limited by the potential toxicity especially from cadmium. Here, a versatile bioimaging probe is developed by using highly luminescent cadmium-free CuInSe

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