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Oncol Lett. 2016 Jul;12(1):601-610. doi: 10.3892/ol.2016.4668. Epub 2016 Jun 01.

Shift in prevalence of HPV types in cervical cytology specimens in the era of HPV vaccination.

Oncology letters

Sonja Fischer, Marcus Bettstetter, Andrea Becher, Marlene Lessel, Cyril Bank, Matthias Krams, Ingrid Becker, Arndt Hartmann, Wolfgang Jagla, Andreas Gaumann

Affiliations

  1. Institute of Pathology Kaufbeuren-Ravensburg, D-87600 Kaufbeuren, Germany.
  2. Part Shared Practice Molecular Pathology South Bavaria, D-81675 Munich, Germany.
  3. Institute of Pathology Kaufbeuren-Ravensburg, D-87600 Kaufbeuren, Germany; Part Shared Practice Molecular Pathology South Bavaria, D-81675 Munich, Germany.
  4. Institute of Pathology Rosenheim, D-83022 Rosenheim, Germany.
  5. Institute of Pathology Erlangen, D-91054 Erlangen, Germany.

PMID: 27347187 PMCID: PMC4907297 DOI: 10.3892/ol.2016.4668

Abstract

The aim of the present population-based cohort study was to analyze the association between the prevalence of 32 types of human papilloma virus (HPV) in 615 female patients with abnormal cervical cytopathology findings. In total, 32 HPV types were screened by DNA array technology. HPV infection was detected in 470 women (76.42%), 419 of whom (89.15%) were infected with ≥1 high-risk (HR)-HPV type. HPV16, which is recognized as the main HR-HPV type responsible for the development of cervical cancer, was observed in 32.98% of HPV

Keywords: HPV16; cervical cancer; high-risk HPV; human papilloma virus; squamous intraepithelial lesions

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