Display options
Cite
Timar B, Timar R, Schiller A, et al. Impact of neuropathy on the adherence to diabetes-related self-care activities: a cross-sectional study. Patient Prefer Adherence. 2016;10:1169-75doi: 10.2147/PPA.S107621.
Timar, B., Timar, R., Schiller, A., Oancea, C., Roman, D., Vlad, M., Balinisteanu, B., & Mazilu, O. (2016). Impact of neuropathy on the adherence to diabetes-related self-care activities: a cross-sectional study. Patient preference and adherence, 101169-75. https://doi.org/10.2147/PPA.S107621
Timar, Bogdan, et al. "Impact of neuropathy on the adherence to diabetes-related self-care activities: a cross-sectional study." Patient preference and adherence vol. 10 (2016): 1169-75. doi: https://doi.org/10.2147/PPA.S107621
Timar B, Timar R, Schiller A, Oancea C, Roman D, Vlad M, Balinisteanu B, Mazilu O. Impact of neuropathy on the adherence to diabetes-related self-care activities: a cross-sectional study. Patient Prefer Adherence. 2016 Jul 01;10:1169-75. doi: 10.2147/PPA.S107621. eCollection 2016. PMID: 27445464; PMCID: PMC4936822.
Copy Download .nbib Format: NLM
Share it on

Patient Prefer Adherence. 2016 Jul 01;10:1169-75. doi: 10.2147/PPA.S107621. eCollection 2016.

Impact of neuropathy on the adherence to diabetes-related self-care activities: a cross-sectional study.

Patient preference and adherence

Bogdan Timar, Romulus Timar, Adalbert Schiller, Cristian Oancea, Deiana Roman, Mihaela Vlad, Bogdan Balinisteanu, Octavian Mazilu

Affiliations

  1. Department of Functional Sciences.
  2. Second Department of Internal Medicine.
  3. Department of Infectious Diseases.
  4. Department of Microscopic Morphology.
  5. First Department of Surgery, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.

PMID: 27445464 PMCID: PMC4936822 DOI: 10.2147/PPA.S107621

Abstract

PURPOSE: The purpose of this study was to evaluate the impact of the presence and severity of neuropathy and depression on the patient's adherence to diabetes-related self-care activities (DRSCA) in a cohort of patients with type 2 diabetes mellitus (T2DM).

PATIENTS AND METHODS: In this cross-sectional, noninterventional study, 198 patients with T2DM were enrolled according to a population-based, consecutive-case enrollment principle. In all patients, the adherence to DRSCA was evaluated using the Summary of Diabetes Self-Care Activities (SDSCA) questionnaire; a higher SDSCA score is associated with a better adherence. The presence and severity of neuropathy was assessed using the Michigan Neuropathy Screening Instrument (MNSI) and the severity of depression using the Patient Health Questionnaire-9 (PHQ-9).

RESULTS: The presence of neuropathy was associated with a decreased SDSCA score (26 points vs 37 points; P<0.001), an increased severe depression prevalence (24.7% vs 4.3%; P<0.001), and an increased PHQ-9 score (12 points vs 7 points; P<0.001). The MNSI score was reverse correlated with SDSCA score (r=-0.527; P<0.001) and positively correlated with PHQ-9 score (r=0.495; P<0.001). The reverse correlation between MNSI score and SDSCA score was present for all the subcomponents of SDSCA questionnaire (diet, exercise, glycemic monitoring, and foot care).

CONCLUSION: The presence of neuropathy is associated with decreases in the quality of adherence to DRSCA in patients with T2DM and with increases in the symptomatology of depression. The significant, negative association between the severity of T2DM and the quality of disease self-management points to a possible loop-type relationship between these two components, being possible a reciprocal augmentation with negative consequences on the global management of the disease.

Keywords: depression; diabetes self-care; diabetic neuropathy; type 2 diabetes mellitus

References

  1. Glob J Health Sci. 2013 Jun 16;5(5):107-14 - PubMed
  2. Diabetologia. 2008 Oct;51(10):1822-5 - PubMed
  3. Diabet Med. 2012 Jul;29(7):937-44 - PubMed
  4. Diabet Med. 2015 Jan;32(1):133-40 - PubMed
  5. JAMA. 2015 Nov 24;314(20):2172-81 - PubMed
  6. Diabetes Care. 2007 Sep;30(9):2222-7 - PubMed
  7. Diabetes Care. 2010 May;33(5):1034-6 - PubMed
  8. JAMA. 1999 Nov 10;282(18):1737-44 - PubMed
  9. Diabet Med. 2008 Oct;25(10):1252-4 - PubMed
  10. Diabetes Care. 2009 Jul;32(7):1177-81 - PubMed
  11. Am J Manag Care. 2004 Feb;10(2 Pt 2):152-62 - PubMed
  12. Diabetes Metab Res Rev. 2015 May;31(4):385-94 - PubMed
  13. J Health Soc Behav. 1999 Jun;40(2):141-58 - PubMed
  14. Cureus. 2015 Aug 12;7(8):e302 - PubMed
  15. Diabetes Care. 2008 Dec;31(12):2398-403 - PubMed
  16. Curr Diabetes Rev. 2015;12(2):114-9 - PubMed
  17. J Psychosom Res. 2014 Apr;76(4):265-74 - PubMed
  18. Diabetes Care. 2010 Jan;33(1):23-8 - PubMed
  19. World J Diabetes. 2015 Feb 15;6(1):80-91 - PubMed
  20. Diabetes Care. 2000 Jul;23(7):934-42 - PubMed
  21. Conf Proc IEEE Eng Med Biol Soc. 2015;2015:2367-70 - PubMed
  22. Rev Diabet Stud. 2015 Spring-Summer;12 (1-2):48-62 - PubMed
  23. Diabetes Care. 2000 Jul;23(7):943-50 - PubMed
  24. Health Qual Life Outcomes. 2013 Aug 13;11:138 - PubMed

Publication Types