Display options
Cite
Loorents V, Rosell J, Salgado Willner H, et al. Health-related quality of life up to 1 year after radiotherapy in patients with head and neck cancer (HNC). Springerplus. 2016;5(1):669doi: 10.1186/s40064-016-2295-1.
Loorents, V., Rosell, J., Salgado Willner, H., & Börjeson, S. (2016). Health-related quality of life up to 1 year after radiotherapy in patients with head and neck cancer (HNC). SpringerPlus, 5(1), 669. https://doi.org/10.1186/s40064-016-2295-1
Loorents, Vera, et al. "Health-related quality of life up to 1 year after radiotherapy in patients with head and neck cancer (HNC)." SpringerPlus vol. 5,1 (2016): 669. doi: https://doi.org/10.1186/s40064-016-2295-1
Loorents V, Rosell J, Salgado Willner H, Börjeson S. Health-related quality of life up to 1 year after radiotherapy in patients with head and neck cancer (HNC). Springerplus. 2016 May 20;5(1):669. doi: 10.1186/s40064-016-2295-1. eCollection 2016. PMID: 27347463; PMCID: PMC4899339.
Copy Download .nbib Format: NLM
Share it on

Springerplus. 2016 May 20;5(1):669. doi: 10.1186/s40064-016-2295-1. eCollection 2016.

Health-related quality of life up to 1 year after radiotherapy in patients with head and neck cancer (HNC).

SpringerPlus

Vera Loorents, Johan Rosell, Helen Salgado Willner, Sussanne Börjeson

Affiliations

  1. Department of Radiation Oncology, Region Ostergotland, Linköping University Hospital, 58185 Linköping, Sweden.
  2. Regional Cancer Center South East Sweden and Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
  3. Department of Radiation Oncology, Region Ostergotland, Linköping University Hospital, 58185 Linköping, Sweden ; Department of Medical and Health Sciences, Linköping University, Linköping, Sweden.

PMID: 27347463 PMCID: PMC4899339 DOI: 10.1186/s40064-016-2295-1

Abstract

BACKGROUND: Detailed symptom specific descriptions of health-related quality of life (HRQOL), using validated questionnaires in patients with head and neck cancer (HNC) are sparse. The aim of the present study was to investigate HRQOL in patients with HNC up to 1 year after radiotherapy (RT), using two standardised questionnaires.

METHODS: The data for the present study was originally collected in a randomised, prospective study. Forty-seven patients from two RT clinics in Sweden were included to investigate the secondary aim: HRQOL. Data was recorded at baseline, completion of RT, and 3, 6, 12 months after completed RT, using the questionnaire EORTC QLQ-C30-version 3 and the disease-specific module EORTC QLQ-H&N35.

RESULTS: Most symptoms and functions deteriorated significantly by the end of RT, improved gradually by 3 and 6 months and reached baseline levels at 12 months after completed RT. However, 1 year after completed RT there were remaining significant problems in senses, dry mouth and sticky saliva.

CONCLUSIONS: Radiation therapy affects health-related quality of life in patients with head and neck cancer, both in the short and long term. Caregivers need management strategies for early detection and treatment of specific problems throughout the treatment period to help in the prevention of long-term symptoms.

Keywords: EORTC QLQ C30; Head and neck cancer; Health-related quality of life; QLQ-H&N35; Trismus

References

  1. J Clin Oncol. 1999 Mar;17(3):1008-19 - PubMed
  2. Crit Rev Oncol Hematol. 2007 Jun;62(3):251-67 - PubMed
  3. J Natl Cancer Inst. 1993 Mar 3;85(5):365-76 - PubMed
  4. Eur J Cancer. 2012 Oct;48(15):2391-408 - PubMed
  5. Laryngoscope. 2001 Aug;111(8):1440-52 - PubMed
  6. Laryngoscope. 2000 Jan;110(1):98-106 - PubMed
  7. Cancer Nurs. 2002 Dec;25(6):461-7; quiz 468-9 - PubMed
  8. Curr Oncol Rep. 2010 May;12(3):208-15 - PubMed
  9. Br J Cancer. 2001 Jan;84(2):149-56 - PubMed
  10. Cancer. 2014 Mar 1;120(5):702-10 - PubMed
  11. J Oral Maxillofac Surg. 2006 Mar;64(3):495-502 - PubMed
  12. Int J Radiat Oncol Biol Phys. 1994 Mar 1;28(4):847-56 - PubMed
  13. CA Cancer J Clin. 2012 Nov-Dec;62(6):400-22 - PubMed
  14. Oral Oncol. 2013 Jun;49(6):634-42 - PubMed
  15. Laryngoscope. 2001 Apr;111(4 Pt 1):669-80 - PubMed
  16. Acta Oncol. 2014 Apr;53(4):530-8 - PubMed

Publication Types