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Teodósio NR, Perez EP, Alves AJ, et al. A New Dietary Supplement Based on Bovine Blood: Recovering Brazilian Children from Malnutrition. Nutr Neurosci. 2000;3(1):73-86doi: 10.1080/1028415X.2000.11747304.
Teodósio, N. R., Perez, E. P., Alves, A. J., Dimenstein, W., & Guedes, R. C. (2000). A New Dietary Supplement Based on Bovine Blood: Recovering Brazilian Children from Malnutrition. Nutritional neuroscience, 3(1), 73-86. https://doi.org/10.1080/1028415X.2000.11747304
Teodósio, N R, et al. "A New Dietary Supplement Based on Bovine Blood: Recovering Brazilian Children from Malnutrition." Nutritional neuroscience vol. 3,1 (2000): 73-86. doi: https://doi.org/10.1080/1028415X.2000.11747304
Teodósio NR, Perez EP, Alves AJ, Dimenstein W, Guedes RC. A New Dietary Supplement Based on Bovine Blood: Recovering Brazilian Children from Malnutrition. Nutr Neurosci. 2000;3(1):73-86. doi: 10.1080/1028415X.2000.11747304. PMID: 27416161.
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Nutr Neurosci. 2000;3(1):73-86. doi: 10.1080/1028415X.2000.11747304.

A New Dietary Supplement Based on Bovine Blood: Recovering Brazilian Children from Malnutrition.

Nutritional neuroscience

N R Teodósio, E P Perez, A J Alves, W Dimenstein, R C Guedes

Affiliations

  1. a Departamento de Nutrição , da Universidade Federal de Pernambuco , Rua Prof. Nelson Chaves, S/N. 50670-901 Recife PE , Brazil.
  2. b Departamento de Pediatria , da Universidade Federal de Pernambuco , Rua Prof. Nelson Chaves, S/N. 50670-901 Recife PE , Brazil.
  3. c Departamento de Ciências Farmacêuticas , da Universidade Federal de Pernambuco , Rua Prof. Nelson Chaves, S/N. 50670-901 Recife PE , Brazil.
  4. d Laboratório Farmaceutico do Estado de Pernambuco (LAFEPE) , 52171-010 Recife PE , Brazil.

PMID: 27416161 DOI: 10.1080/1028415X.2000.11747304

Abstract

Two compounds ("Prothemol" and "Plasmel"), based on bovine blood as source of high quality-protein, were tested as supplement for malnourished children. Prothemol is a powder containing desiccated bovine red cells, with 23.32 g% protein and 18.8 mg% iron, without any limiting amino acid. Plasmel (a syrup) contains 44.7% bovine plasma, 54.3% saccharose and 1500 IU% retinol. Children, 32-60 month old, from a day-nursery service in Recife, Brazil, received Prothemol + Plasmel for 90 (n = 14) or 180 days (n = 8). When compared to age-matched control children (n = 12 and n = 6, respectively), they presented significantly higher increments in weight and height, and in some haematological parameters. Clinical signs associated to malnutrition (faces suggesting suffering or sadness; brightnessless eyes; apathy; reduced mobility; reduced communication with their classmates and adults) were found in 12 treated children (85.7%) and in 9 controls (75%). Recovery from these signs begun after 51 ± 20.6 and 103.5 ± 14.6 days, for the treated and control groups, respectively (P < 0.05) and occurred in 100% of the treated children and in 67% (6 of 9 children) in the controls. We suggest that Prothemol + Plasmel is an effective dietary supplement to help treating malnutrition in children, recovering them from clinical signs indicative of improving neural functions.

Keywords: Bovine blood; Development; Essential amino acids; Malnutrition; Prothemol + Plasmel

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