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Biomed Opt Express. 2016 Mar 24;7(4):1468-78. doi: 10.1364/BOE.7.001468. eCollection 2016 Apr 01.

Photoacoustic clutter reduction by inversion of a linear scatter model using plane wave ultrasound measurements.

Biomedical optics express

Hans-Martin Schwab, Martin F Beckmann, Georg Schmitz

Affiliations

  1. Medical Engineering, Ruhr-Universität Bochum, Bochum, 44780, Germany.

PMID: 27446669 PMCID: PMC4929655 DOI: 10.1364/BOE.7.001468

Abstract

Photoacoustic imaging aims to visualize light absorption properties of biological tissue by receiving a sound wave that is generated inside the observed object as a result of the photoacoustic effect. In clinical applications, the strong light absorption in human skin is a major problem. When high amplitude photoacoustic waves that originate from skin absorption propagate into the tissue, they are reflected back by acoustical scatterers and the reflections contribute to the received signal. The artifacts associated with these reflected waves are referred to as clutter or skin echo and limit the applicability of photoacoustic imaging for medical applications severely. This study seeks to exploit the acoustic tissue information gained by plane wave ultrasound measurements with a linear array in order to correct for reflections in the photoacoustic image. By deriving a theory for clutter waves in k-space and a matching inversion approach, photoacoustic measurements compensated for clutter are shown to be recovered.

Keywords: (100.3190) Inverse problems; (110.3200) Inverse scattering; (110.5120) Photoacoustic imaging; (170.0170) Medical optics and biotechnology; (170.7170) Ultrasound

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