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Sheikhzadeh M, Lotfi Y, Mousavi A, et al. Influence of supplemental vitamin D on intensity of benign paroxysmal positional vertigo: A longitudinal clinical study. Caspian J Intern Med. 2016;7(2):93-8
Sheikhzadeh, M., Lotfi, Y., Mousavi, A., Heidari, B., Monadi, M., & Bakhshi, E. (2016). Influence of supplemental vitamin D on intensity of benign paroxysmal positional vertigo: A longitudinal clinical study. Caspian journal of internal medicine, 7(2), 93-8.
Sheikhzadeh, Mahboobeh, et al. "Influence of supplemental vitamin D on intensity of benign paroxysmal positional vertigo: A longitudinal clinical study." Caspian journal of internal medicine vol. 7,2 (2016): 93-8.
Sheikhzadeh M, Lotfi Y, Mousavi A, Heidari B, Monadi M, Bakhshi E. Influence of supplemental vitamin D on intensity of benign paroxysmal positional vertigo: A longitudinal clinical study. Caspian J Intern Med. 2016;7(2):93-8. PMID: 27386060; PMCID: PMC4913711.
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Caspian J Intern Med. 2016;7(2):93-8.

Influence of supplemental vitamin D on intensity of benign paroxysmal positional vertigo: A longitudinal clinical study.

Caspian journal of internal medicine

Mahboobeh Sheikhzadeh, Yones Lotfi, Abdollah Mousavi, Behzad Heidari, Mohsen Monadi, Enayatollah Bakhshi

Affiliations

  1. Department of Audiology, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
  2. University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
  3. Tehran University of Medical Sciences, Tehran, Iran.
  4. Mobility Impairment Research Center, Babol University of Medical Sciences, Babol, Iran.
  5. Department of Audiology, Babol University of Medical Sciences, Babol, Iran.
  6. Department of Statistics, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.

PMID: 27386060 PMCID: PMC4913711

Abstract

BACKGROUND: Benign paroxysmal positional vertigo (BPPV) is linked to vitamin D deficiency. This clinical trial aimed to determine the influence of vitamin D supplementation on intensity of BPPV.

METHODS: The study population was selected consecutively and the diagnosis of BPPV was made by history and clinical examination and exclusion of other conditions. Intensity of BPVV was assessed based on VAS score (0-10). Serum 25-hydroxyvitamin D (25-OHD) was measured using ELISA method and levels < 20 ng/ml was considered a deficiency. All patients received rehabilitation treatment using Epley's maneuver one time per week for one month. Serum 25-OHD deficient patients were classified as treated and non-treated groups (rehabilitation with or without 50.000 IU cholecalciferol weekly for two months).The results of treatment were compared with vitamin D sufficient group as control. All patients were followed-up for 6 months.

RESULTS: After two months of treatment, in both vitamin D treated and non-treated groups the intensity of BPPV decreased significantly as compared with control (P=0.001 for both groups) but at endpoint, the intensity of BPPV aggravated and regressed to the baseline value in vitamin D deficient non-treated group (P=0.001) whereas, in vitamin D treated group, improvement of BPPV remained stable and unchanged over the study period.

CONCLUSION: This study indicates that correction of vitamin D deficiency in BPPV provides additional benefit to rehabilitation therapy (Epley maneuver) regarding duration of improvement. These findings suggest serum 25-OHD measurement in recurrent BPPV.

Keywords: Benign paroxysmal positional vertigo; Intensity; Rehabilitation Therapy.; Vitamin D

References

  1. BMC Neurol. 2009 Jul 07;9:29 - PubMed
  2. Acta Med Iran. 2015 Aug;53(8):466-70 - PubMed
  3. Diabetes Metab Syndr. 2014 Jul-Sep;8(3):170-6 - PubMed
  4. Otolaryngol Head Neck Surg. 2000 May;122(5):647-52 - PubMed
  5. East Mediterr Health J. 2010 Aug;16(8):868-73 - PubMed
  6. Clin Calcium. 2011 Nov;21(11):71-9 - PubMed
  7. Cochrane Database Syst Rev. 2004;(2):CD003162 - PubMed
  8. J Am Geriatr Soc. 2011 Dec;59(12):2291-300 - PubMed
  9. Laryngoscope. 2013 Nov;123(11):2834-9 - PubMed
  10. BMJ. 2009 Oct 01;339:b3692 - PubMed
  11. Menopause. 2016 Mar;23 (3):267-74 - PubMed
  12. Aging Dis. 2014 Feb 09;6(1):38-47 - PubMed
  13. Obes Rev. 2007 Jan;8(1):3-10 - PubMed
  14. Iran J Public Health. 2013 Nov;42(11):1283-91 - PubMed
  15. Acta Otorrinolaringol Esp. 2015 Jul-Aug;66(4):205-9 - PubMed
  16. BMC Neurol. 2014 May 20;14:110 - PubMed
  17. Caspian J Intern Med. 2015 Spring;6(2):93-7 - PubMed
  18. Eur Arch Otorhinolaryngol. 2016 Mar;273(3):573-80 - PubMed
  19. PLoS One. 2013 Dec 03;8(12):e80176 - PubMed
  20. J Nutr Health Aging. 2011 May;15(5):349-54 - PubMed
  21. Caspian J Intern Med. 2011 Summer;2(3):249-55 - PubMed
  22. J Neurol. 2013 Mar;260(3):832-8 - PubMed
  23. Ther Adv Chronic Dis. 2011 Jan;2(1):25-37 - PubMed
  24. Caspian J Intern Med. 2011 Spring;2(2):205-12 - PubMed
  25. J Nutr Health Aging. 2012 Mar;16(3):270-5 - PubMed
  26. J Reprod Med. 2013 Sep-Oct;58(9-10):389-94 - PubMed
  27. Eur Arch Otorhinolaryngol. 2005 Jun;262(6):507-11 - PubMed
  28. Acta Med Iran. 2014;52(5):400-5 - PubMed
  29. Public Health Nutr. 2012 Dec;15(12):2246-52 - PubMed
  30. Diabetes Metab Syndr. 2016 Apr-Jun;10 (2):105-12 - PubMed
  31. Caspian J Intern Med. 2012 Fall;3(4):535-40 - PubMed
  32. Auris Nasus Larynx. 2016 Jun;43(3):237-41 - PubMed
  33. Eur Arch Otorhinolaryngol. 2015 Sep;272(9):2249-53 - PubMed

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