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Hum Pathol (N Y). 2016 Sep;5:6-9. doi: 10.1016/j.ehpc.2015.10.001.

Chronic eosinophilic leukemia, NOS with t(5;12)(q31;p13)/ETV6-ACSL6 gene fusion: a novel variant of myeloid proliferative neoplasm with eosinophilia.

Human pathology (New York)

Ruijun Jeanna Su, Brian A Jonas, Jeanna Welborn, Jeffrey Paul Gregg, Mingyi Chen

Affiliations

  1. Department of Pathology and Laboratory Medicine, University of California at Davis Medical Center, Sacramento, CA 95817.
  2. Division of Hematology and Oncology, University of California at Davis Medical Center, Sacramento, CA 95817.

PMID: 27458550 PMCID: PMC4957580 DOI: 10.1016/j.ehpc.2015.10.001

Abstract

The 2008 World Health Organization (WHO) classification of tumors of hematopoietic and lymphoid tissues introduced a category for myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB or FGFR1. Many of these patients are responsive to tyrosine kinase inhibitor (TKI) therapy. In this

Keywords: Chronic eosinophilic leukemia; Myeloid proliferative neoplasm with eosinophilia; NOS; Novel ETV6-ACSL6 gene fusion

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