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Akdag S, Akyol A, Asker M, et al. The relation of platelet-lymphocyte ratio and coronary collateral circulation in patients with non-ST segment elevation myocardial infarction. Postepy Kardiol Interwencyjnej. 2016;12(3):224-30doi: 10.5114/aic.2016.61644.
Akdag, S., Akyol, A., Asker, M., Ozturk, F., & Gumrukcuoglu, H. A. (2016). The relation of platelet-lymphocyte ratio and coronary collateral circulation in patients with non-ST segment elevation myocardial infarction. Postepy w kardiologii interwencyjnej = Advances in interventional cardiology, 12(3), 224-30. https://doi.org/10.5114/aic.2016.61644
Akdag, Serkan, et al. "The relation of platelet-lymphocyte ratio and coronary collateral circulation in patients with non-ST segment elevation myocardial infarction." Postepy w kardiologii interwencyjnej = Advances in interventional cardiology vol. 12,3 (2016): 224-30. doi: https://doi.org/10.5114/aic.2016.61644
Akdag S, Akyol A, Asker M, Ozturk F, Gumrukcuoglu HA. The relation of platelet-lymphocyte ratio and coronary collateral circulation in patients with non-ST segment elevation myocardial infarction. Postepy Kardiol Interwencyjnej. 2016;12(3):224-30. doi: 10.5114/aic.2016.61644. Epub 2016 Aug 19. PMID: 27625685; PMCID: PMC5011538.
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Postepy Kardiol Interwencyjnej. 2016;12(3):224-30. doi: 10.5114/aic.2016.61644. Epub 2016 Aug 19.

The relation of platelet-lymphocyte ratio and coronary collateral circulation in patients with non-ST segment elevation myocardial infarction.

Postepy w kardiologii interwencyjnej = Advances in interventional cardiology

Serkan Akdag, Aytac Akyol, Muntecep Asker, Fatih Ozturk, Hasan Ali Gumrukcuoglu

Affiliations

  1. Department of Cardiology, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey.

PMID: 27625685 PMCID: PMC5011538 DOI: 10.5114/aic.2016.61644

Abstract

INTRODUCTION: Recently, platelet-to-lymphocyte ratio (PLR) has emerged as a significant inflammatory marker and a novel predictor of major adverse consequences in cardiovascular disease.

AIM: In this study, we aimed to explore the relationship between PLR and coronary collateral circulation (CCC) in patients with non-ST elevation myocardial infarction (NSTEMI).

MATERIAL AND METHODS: Clinical and laboratory data of 386 patients who underwent coronary angiography were evaluated retrospectively. The patients were classified into 2 groups as follows: poor CCC (group 1: Rentrop grades 0-1) and good CCC (group 2: Rentrop grades 2-3). The PLR was calculated from the complete blood count.

RESULTS: The PLR values of the patients with poor CCC were significantly higher than those of patients with good CCC (153.9 ±26.6 vs. 129.8 ±23.5, p < 0.001). In the multiple logistic regression tests, PLR (odds ratio: 1.51, 95% confidence interval: 1.27-1.74; p < 0.001) and hs-CRP (odds ratio: 1.56, 95% CI: 1.03-2.11; p < 0.001) were found to be independent predictors of poor CCC. The receiver operating characteristic (ROC) curve analysis yielded a cutoff value of 140.5 for PLR to predict poor CCC with 79% sensitivity and 71% specificity, with the area under the ROC curve being 0.792 (95% CI: 0.721-0.864).

CONCLUSIONS: Our study revealed that high PLR is independently associated with poor coronary collateral circulation in patients with NSTEMI.

Keywords: angiography; cardiology; coronary artery disease

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