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Galante J, Iribarren SJ, Pearce PF. Effects of mindfulness-based cognitive therapy on mental disorders: a systematic review and meta-analysis of randomised controlled trials. J Res Nurs. 2012;18(2):133-155doi: 10.1177/1744987112466087.
Galante, J., Iribarren, S. J., & Pearce, P. F. (2013). Effects of mindfulness-based cognitive therapy on mental disorders: a systematic review and meta-analysis of randomised controlled trials. Journal of research in nursing : JRN, 18(2), 133-155. https://doi.org/10.1177/1744987112466087
Galante, Julieta, et al. "Effects of mindfulness-based cognitive therapy on mental disorders: a systematic review and meta-analysis of randomised controlled trials." Journal of research in nursing : JRN vol. 18,2 (2013): 133-155. doi: https://doi.org/10.1177/1744987112466087
Galante J, Iribarren SJ, Pearce PF. Effects of mindfulness-based cognitive therapy on mental disorders: a systematic review and meta-analysis of randomised controlled trials. J Res Nurs. 2013 Mar;18(2):133-155. doi: 10.1177/1744987112466087. Epub 2012 Nov 29. PMID: 27660642; PMCID: PMC5030069.
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J Res Nurs. 2013 Mar;18(2):133-155. doi: 10.1177/1744987112466087. Epub 2012 Nov 29.

Effects of mindfulness-based cognitive therapy on mental disorders: a systematic review and meta-analysis of randomised controlled trials.

Journal of research in nursing : JRN

Julieta Galante, Sarah J Iribarren, Patricia F Pearce

Affiliations

  1. PhD candidate, Institute of Primary Care and Public Health, Cardiff University, UK.
  2. Nursing PhD candidate, College of Nursing, University of Utah, USA.
  3. Associate Professor, School of Nursing, Loyola University, New Orleans, USA.

PMID: 27660642 PMCID: PMC5030069 DOI: 10.1177/1744987112466087

Abstract

OBJECTIVE: Mindfulness-based cognitive therapy (MBCT) is a programme developed to prevent depression relapse, but has been applied for other disorders. Our objective was to systematically review and meta-analyse the evidence on the effectiveness and safety of MBCT for the treatment of mental disorders.

METHODS: Searches were completed in CENTRAL, MEDLINE, EMBASE, LILACS, PsychINFO, and PsycEXTRA in March 2011 using a search strategy with the terms 'mindfulness-based cognitive therapy', 'mindfulness', and 'randomised controlled trials' without time restrictions. Selection criteria of having a randomised controlled trial design, including patients diagnosed with mental disorders, using MBCT according to the authors who developed MBCT and providing outcomes that included changes in mental health were used to assess 608 reports. Two reviewers applied the pre-determined selection criteria and extracted the data into structured tables. Meta-analyses and sensitivity analyses were completed.

RESULTS: Eleven studies were included. Most of them evaluated depression and compared additive MBCT against usual treatment. After 1 year of follow-up MBCT reduced the rate of relapse in patients with three or more previous episodes of depression by 40% (5 studies, relative risk [95% confidence interval]: 0.61 [0.48, 0.79]). Other meta-analysed outcomes were depression and anxiety, both with significant results but unstable in sensitivity analyses. Methodological quality of the reports was moderate.

CONCLUSION: Based on this review and meta-analyses, MBCT is an effective intervention for patients with three or more previous episodes of major depression.

Keywords: depression; mental disorders; meta-analysis; mindfulness-based cognitive therapy; randomised controlled trials; systematic review

Conflict of interest statement

statement None declared.

References

  1. Behav Res Ther. 2010 Aug;48(8):738-46 - PubMed
  2. Emotion. 2010 Feb;10(1):34-42 - PubMed
  3. Br J Soc Clin Psychol. 1967 Dec;6(4):278-96 - PubMed
  4. J Affect Disord. 2010 May;122(3):224-31 - PubMed
  5. J Consult Clin Psychol. 2002 Apr;70(2):275-87 - PubMed
  6. Psychiatry Res. 2005 Jun 30;135(3):229-35 - PubMed
  7. Psychiatry Res. 2011 May 30;187(3):441-53 - PubMed
  8. Clin Psychol Rev. 2011 Aug;31(6):1032-40 - PubMed
  9. J Consult Clin Psychol. 2010 Feb;78(1):72-9 - PubMed
  10. Br J Clin Psychol. 2009 Jun;48(Pt 2):209-15 - PubMed
  11. J Abnorm Psychol. 2000 Feb;109(1):150-5 - PubMed
  12. J Pers Assess. 1996 Dec;67(3):588-97 - PubMed
  13. J Consult Clin Psychol. 2004 Feb;72(1):31-40 - PubMed
  14. J Consult Clin Psychol. 2007 Dec;75(6):1000-5 - PubMed
  15. J Consult Clin Psychol. 2008 Dec;76(6):966-78 - PubMed
  16. Lancet. 1999 Nov 27;354(9193):1896-900 - PubMed
  17. Scand J Psychol. 2010 Oct;51(5):403-10 - PubMed
  18. J Consult Clin Psychol. 2000 Aug;68(4):615-23 - PubMed
  19. Subst Abus. 2010 Apr;31(2):86-97 - PubMed
  20. Br J Psychiatry. 2010 Nov;197(5):345-7 - PubMed
  21. Behav Res Ther. 2009 May;47(5):366-73 - PubMed
  22. Acta Psychiatr Scand. 2011 Aug;124(2):102-19 - PubMed
  23. Arch Psychiatr Nurs. 2004 Oct;18(5):164-9 - PubMed
  24. J Consult Clin Psychol. 2008 Jun;76(3):524-9 - PubMed
  25. J Consult Clin Psychol. 2010 Apr;78(2):169-83 - PubMed
  26. Arch Gen Psychiatry. 2010 Dec;67(12):1256-64 - PubMed
  27. Neuroreport. 2007 May 7;18(7):709-12 - PubMed

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