Display options
Cite
Edwards AM, Cameron EZ, Pereira JC, et al. Gestational experience alters sex allocation in the subsequent generation. R Soc Open Sci. 2016;3(7):160210doi: 10.1098/rsos.160210.
Edwards, A. M., Cameron, E. Z., Pereira, J. C., Wapstra, E., Ferguson-Smith, M. A., Horton, S. R., & Thomasson, K. (2016). Gestational experience alters sex allocation in the subsequent generation. Royal Society open science, 3(7), 160210. https://doi.org/10.1098/rsos.160210
Edwards, A M, et al. "Gestational experience alters sex allocation in the subsequent generation." Royal Society open science vol. 3,7 (2016): 160210. doi: https://doi.org/10.1098/rsos.160210
Edwards AM, Cameron EZ, Pereira JC, Wapstra E, Ferguson-Smith MA, Horton SR, Thomasson K. Gestational experience alters sex allocation in the subsequent generation. R Soc Open Sci. 2016 Jul 13;3(7):160210. doi: 10.1098/rsos.160210. eCollection 2016 Jul. PMID: 27493776; PMCID: PMC4968468.
Copy Download .nbib Format: NLM
Share it on

R Soc Open Sci. 2016 Jul 13;3(7):160210. doi: 10.1098/rsos.160210. eCollection 2016 Jul.

Gestational experience alters sex allocation in the subsequent generation.

Royal Society open science

A M Edwards, E Z Cameron, J C Pereira, E Wapstra, M A Ferguson-Smith, S R Horton, K Thomasson

Affiliations

  1. School of Biological Sciences, University of Tasmania, Hobart, Tasmania, Australia; Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
  2. School of Biological Sciences , University of Tasmania , Hobart, Tasmania , Australia.
  3. Department of Veterinary Medicine, University of Cambridge, Cambridge, UK; Cytocell Ltd., Cambridge Technopark, Newmarket Road, Cambridge, UK.
  4. Department of Veterinary Medicine , University of Cambridge , Cambridge , UK.

PMID: 27493776 PMCID: PMC4968468 DOI: 10.1098/rsos.160210

Abstract

Empirical tests of adaptive maternal sex allocation hypotheses have presented inconsistent results in mammals. The possibility that mothers are constrained in their ability to adjust sex ratios could explain some of the remaining variation. Maternal effects, the influence of the maternal phenotype or genotype on her developing offspring, may constrain sex allocation through physiological changes in response to the gestational environment. We tested if maternal effects constrain future parental sex allocation through a lowered gestational stress environment in laboratory mice. Females that experienced lowered stress as embryos in utero gave birth to female-biased litters as adults, with no change to litter size. Changes in offspring sex ratio was linked to peri-conceptual glucose, as those females that had increasing blood glucose peri-conceptionally gave birth to litters with a higher male to female sex ratio. There was, however, no effect of the lowered prenatal stress for developing male embryos and their sperm sex ratio when adult. We discuss the implications of maternal effects and maternal stress environment on the lifelong physiology of the offspring, particularly as a constraint on later maternal sex allocation.

Keywords: fluorescent in situ hybridization; maternal; paternal; sex allocation; sex ratio

References

  1. J Physiol. 2006 Apr 1;572(Pt 1):25-30 - PubMed
  2. Proc Biol Sci. 2004 Aug 22;271(1549):1723-8 - PubMed
  3. Eur J Endocrinol. 2004 Nov;151 Suppl 3:U49-62 - PubMed
  4. J Comp Physiol B. 2010 Aug;180(6):785-96 - PubMed
  5. Biol Reprod. 2008 May;78(5):812-5 - PubMed
  6. Arch Sex Behav. 2008 Feb;37(1):9-18 - PubMed
  7. Ann N Y Acad Sci. 2004 Dec;1032:63-84 - PubMed
  8. Science. 1978 Jul 14;201(4351):163-5 - PubMed
  9. Am J Physiol. 1993 Jan;264(1 Pt 1):E119-27 - PubMed
  10. J Neurosci. 1998 Apr 1;18(7):2570-80 - PubMed
  11. Ann N Y Acad Sci. 2004 Jun;1024:1-8 - PubMed
  12. Science. 2006 Dec 1;314(5804):1445-7 - PubMed
  13. J Dev Orig Health Dis. 2015 Apr;6(2):127-42 - PubMed
  14. Physiol Rev. 1992 Oct;72(4):1063-81 - PubMed
  15. Trends Ecol Evol. 2014 Mar;29(3):158-64 - PubMed
  16. J Theor Biol. 1984 May 21;108(2):203-13 - PubMed
  17. Proc Biol Sci. 2007 Mar 7;274(1610):727-33 - PubMed
  18. Neuroscience. 2011 Oct 13;193:34-43 - PubMed
  19. Front Endocrinol (Lausanne). 2014 May 13;5:73 - PubMed
  20. J Endocrinol. 2008 Jul;198(1):3-15 - PubMed
  21. J Anim Ecol. 2009 Nov;78(6):1249-58 - PubMed
  22. Q Rev Biol. 1986 Sep;61(3):339-74 - PubMed
  23. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9677-82 - PubMed
  24. Dev Psychobiol. 2011 Jan;53(1):69-78 - PubMed
  25. Behav Neural Biol. 1990 Jul;54(1):1-12 - PubMed
  26. Trends Ecol Evol. 1998 Oct 1;13(10):403-7 - PubMed
  27. Reproduction. 2010 Sep;140(3):425-33 - PubMed
  28. Brain Behav Immun. 2005 Jul;19(4):296-308 - PubMed
  29. BMJ. 2000 Dec 23-30;321(7276):1609-12 - PubMed
  30. Philos Trans R Soc Lond B Biol Sci. 2009 Apr 27;364(1520):1107-15 - PubMed
  31. Proc Biol Sci. 2008 Feb 7;275(1632):323-7 - PubMed
  32. Am J Physiol Regul Integr Comp Physiol. 2005 Jan;288(1):R34-8 - PubMed
  33. Science. 1967 Apr 28;156(3774):477-88 - PubMed
  34. Science. 1973 Jan 5;179(4068):90-2 - PubMed
  35. Horm Behav. 2011 Mar;59(3):279-89 - PubMed
  36. Mol Reprod Dev. 2005 Oct;72(2):201-7 - PubMed
  37. Brain Res. 1991 Aug 30;558(1):75-8 - PubMed
  38. J Theor Biol. 2013 Oct 7;334:141-8 - PubMed
  39. Hum Reprod. 1996 Nov;11(11):2371-5 - PubMed
  40. J Endocrinol. 2001 Sep;170(3):653-60 - PubMed
  41. Am Nat. 2004 Jan;163(1):40-54 - PubMed
  42. Endocrinology. 2008 Dec;149(12):6343-55 - PubMed
  43. Endocrinology. 1969 Nov;85(5):811-4 - PubMed
  44. Neuroscience. 2001;104(1):71-9 - PubMed
  45. Am Nat. 2008 Oct;172(4):E135-49 - PubMed
  46. Reprod Fertil Dev. 2001;13(5-6):361-5 - PubMed
  47. Evolution. 2016 Feb;70(2):358-68 - PubMed
  48. J Theor Biol. 2007 Jun 21;246(4):708-19 - PubMed
  49. J Physiol. 2010 Mar 1;588(Pt 5):887-99 - PubMed
  50. J Physiol. 2006 Apr 1;572(Pt 1):31-44 - PubMed
  51. J Endocrinol. 2013 Apr 15;217(2):161-73 - PubMed
  52. J Neuroendocrinol. 2010 Nov;22(11):1198-213 - PubMed
  53. J Nutr. 1998 Feb;128(2 Suppl):401S-406S - PubMed

Publication Types