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Siński M, Lewandowski J, Dobosiewicz A, et al. The effect of hyperoxia on central blood pressure in healthy subjects. Arch Med Sci. 2016;12(5):992-999doi: 10.5114/aoms.2015.49038.
Siński, M., Lewandowski, J., Dobosiewicz, A., Przybylski, J., Abramczyk, P., & Gaciong, Z. (2016). The effect of hyperoxia on central blood pressure in healthy subjects. Archives of medical science : AMS, 12(5), 992-999. https://doi.org/10.5114/aoms.2015.49038
Siński, Maciej, et al. "The effect of hyperoxia on central blood pressure in healthy subjects." Archives of medical science : AMS vol. 12,5 (2016): 992-999. doi: https://doi.org/10.5114/aoms.2015.49038
Siński M, Lewandowski J, Dobosiewicz A, Przybylski J, Abramczyk P, Gaciong Z. The effect of hyperoxia on central blood pressure in healthy subjects. Arch Med Sci. 2016 Oct 01;12(5):992-999. doi: 10.5114/aoms.2015.49038. Epub 2016 Aug 24. PMID: 27695489; PMCID: PMC5016570.
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Arch Med Sci. 2016 Oct 01;12(5):992-999. doi: 10.5114/aoms.2015.49038. Epub 2016 Aug 24.

The effect of hyperoxia on central blood pressure in healthy subjects.

Archives of medical science : AMS

Maciej Siński, Jacek Lewandowski, Anna Dobosiewicz, Jacek Przybylski, Piotr Abramczyk, Zbigniew Gaciong

Affiliations

  1. Department of Internal Medicine, Hypertension and Vascular Diseases, Medical University of Warsaw, Warsaw, Poland.
  2. Department of Pulmonary Circulation and Thromboembolic Diseases, Center of Postgraduate Medical Education, Otwock, Poland.
  3. Department of Biophysics and Physiology, Medical University of Warsaw, Warsaw, Poland.

PMID: 27695489 PMCID: PMC5016570 DOI: 10.5114/aoms.2015.49038

Abstract

INTRODUCTION: Hyperoxia increases total peripheral resistance by acting locally but also inhibits the activity of carotid body chemoreceptors. We studied the effect of hyperoxia on central pressure in normotensive subjects.

MATERIAL AND METHODS: Medical air followed by 100% oxygen was provided to 19 subjects (12/7 female/male, age 28.2 ±1.1 years) for 15 min through a non-rebreather mask. Central blood pressure was then measured using applanation tonometry.

RESULTS: After the first 2 min of hyperoxia, heart rate decreased significantly (65 ±2.6 beats/min vs. 61 ±2.1 beats/min,

CONCLUSIONS: The present study shows that hyperoxia does not affect central blood pressure in young healthy subjects and may improve myocardial blood supply estimated indirectly from applanation tonometry.

Keywords: carotid body chemoreceptors; central blood pressure; hyperoxia

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