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Plant Cell. 2016 Sep;28(9):2043-2059. doi: 10.1105/tpc.16.00474. Epub 2016 Aug 16.

DNA DAMAGE BINDING PROTEIN2 Shapes the DNA Methylation Landscape.

The Plant cell

Catherine Schalk, Stéphanie Drevensek, Amira Kramdi, Mohamed Kassam, Ikhlak Ahmed, Valérie Cognat, Stéfanie Graindorge, Marc Bergdoll, Nicolas Baumberger, Dimitri Heintz, Chris Bowler, Pascal Genschik, Fredy Barneche, Vincent Colot, Jean Molinier

Affiliations

  1. Institut de Biologie Moléculaire de Plantes du CNRS, UPR 2357, F-67084 Strasbourg, France.
  2. Ecole Normale Supérieure, PSL Research University, Institut de Biologie de l'Ecole Normale Supérieure, CNRS UMR 8197, INSERM U1024, F-75005 Paris, France.
  3. Institut de Biologie Moléculaire de Plantes du CNRS, UPR 2357, F-67084 Strasbourg, France [email protected].

PMID: 27531226 PMCID: PMC5059809 DOI: 10.1105/tpc.16.00474

Abstract

In eukaryotes, DNA repair pathways help to maintain genome integrity and epigenomic patterns. However, the factors at the nexus of DNA repair and chromatin modification/remodeling remain poorly characterized. Here, we uncover a previously unrecognized interplay between the DNA repair factor DNA DAMAGE BINDING PROTEIN2 (DDB2) and the DNA methylation machinery in

© 2016 American Society of Plant Biologists. All rights reserved.

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