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Mol Clin Oncol. 2016 Oct;5(4):391-394. doi: 10.3892/mco.2016.977. Epub 2016 Aug 04.

Efficacy and safety of oxaliplatin, bevacizumab and oral S-1 for advanced recurrent colorectal cancer.

Molecular and clinical oncology

Shuji Suzuki, Jiro Shimazaki, Keiichi Morishita, Nobusada Koike, Nobuhiko Harada, Tsuneo Hayashi, Mamoru Suzuki

Affiliations

  1. Department of Gastroenterological Surgery, Ibaraki Medical Center, Tokyo Medical University, Amimachi, Ibaraki 300-0395, Japan.
  2. Department of Surgery, Hachioji Digestive Disease Hospital, Hachioji, Tokyo 192-0903, Japan.

PMID: 27699032 PMCID: PMC5038216 DOI: 10.3892/mco.2016.977

Abstract

The aim of this study was to evaluate the efficacy and safety of co-administration of oral S-1 and oxaliplatin (SOX) in combination with bevacizumab (bev) in patients with advanced recurrent colorectal cancer. A retrospective study of 36 patients with advanced recurrent colorectal cancer was performed, of whom 27 received first-line and 9 received second-line SOX+bev chemotherapy between 2010 and 2013 at the Hachioji Digestive Disease Hospital (Hachioji, Japan). The SOX+bev regimen consisted of administration of intravenous oxaliplatin (85 mg/m

Keywords: S-1; SOX+bev; bevacizumab; colorectal cancer; oxaliplatin

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