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Org Lett. 2016 Oct 21;18(20):5252-5255. doi: 10.1021/acs.orglett.6b02549. Epub 2016 Oct 04.

Expedient Cobalt-Catalyzed C-H Alkynylation of (Enantiopure) Benzylamines.

Organic letters

Vinod G Landge, Siba P Midya, Jagannath Rana, Dinesh R Shinde, Ekambaram Balaraman

Affiliations

  1. Academy of Scientific and Innovative Research , New Delhi 110 025, India.

PMID: 27700123 DOI: 10.1021/acs.orglett.6b02549

Abstract

A unified strategy for cobalt-catalyzed ortho-C-H bond alkynylation of benzylamines is reported. Simple, commercially available CoBr

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