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Damm R, Mohnike K, Gazis A, et al. Improvement of Contrast Media Enhancement in CTA Evaluating Pulmonary Embolism by Utilizing 'Delayed' Bolus Tracking in the Descending Aorta. Pol J Radiol. 2016;81:422-7doi: 10.12659/PJR.897456.
Damm, R., Mohnike, K., Gazis, A., Rogits, B., Seidensticker, M., Ricke, J., & Pech, M. (2016). Improvement of Contrast Media Enhancement in CTA Evaluating Pulmonary Embolism by Utilizing 'Delayed' Bolus Tracking in the Descending Aorta. Polish journal of radiology, 81422-7. https://doi.org/10.12659/PJR.897456
Damm, Robert, et al. "Improvement of Contrast Media Enhancement in CTA Evaluating Pulmonary Embolism by Utilizing 'Delayed' Bolus Tracking in the Descending Aorta." Polish journal of radiology vol. 81 (2016): 422-7. doi: https://doi.org/10.12659/PJR.897456
Damm R, Mohnike K, Gazis A, Rogits B, Seidensticker M, Ricke J, Pech M. Improvement of Contrast Media Enhancement in CTA Evaluating Pulmonary Embolism by Utilizing 'Delayed' Bolus Tracking in the Descending Aorta. Pol J Radiol. 2016 Sep 05;81:422-7. doi: 10.12659/PJR.897456. eCollection 2016. PMID: 27668026; PMCID: PMC5022633.
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Pol J Radiol. 2016 Sep 05;81:422-7. doi: 10.12659/PJR.897456. eCollection 2016.

Improvement of Contrast Media Enhancement in CTA Evaluating Pulmonary Embolism by Utilizing 'Delayed' Bolus Tracking in the Descending Aorta.

Polish journal of radiology

Robert Damm, Konrad Mohnike, Angelos Gazis, Bela Rogits, Max Seidensticker, Jens Ricke, Maciej Pech

Affiliations

  1. Department for Radiology and Nuclear Medicine, University of Magdeburg, Magdeburg, Germany.

PMID: 27668026 PMCID: PMC5022633 DOI: 10.12659/PJR.897456

Abstract

BACKGROUND: As standard bolus triggering in the pulmonary trunk sometimes fails to achieve sufficient enhancement in the pulmonary arteries, the study investigates an alternative, 'delayed' position of the tracking ROI in the descending aorta.

MATERIAL/METHODS: Retrospective analysis of 143 patients suspected of pulmonary embolism investigated with 3 different scanners (16 to 80 rows) in clinical routine. Bolus triggering with 120 hounsfield units (HU) was performed using the pulmonary trunk (n=70) or descending aorta (n=73) after application of 70 to 120 mL of contrast agent, Iomeprol 300. Student's t-test was applied to compare vascular enhancement. Additional factors were analysed by a regression analysis.

RESULTS: Positioning of the tracking ROI in the descending aorta achieved a significantly higher contrast enhancement in the pulmonary trunk with a mean increase of 63 HU (p<0.001).

CONCLUSIONS: In CTA, delayed acquisition by using the descending aorta for bolus triggering can improve the enhancement of the pulmonary trunk to investigate a pulmonary embolism. Furthermore, the scan protocol simultaneously allows to rule out aortic pathologies as an alternative cause for a similar clinical condition.

Keywords: Contrast Media; Multidetector Computed Tomography; Pulmonary Embolism

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