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Di Vitantonio H, De Paulis D, Del Maestro M, et al. Dural repair using autologous fat: Our experience and review of the literature. Surg Neurol Int. 2016;7:S463-8doi: 10.4103/2152-7806.185777.
Di Vitantonio, H., De Paulis, D., Del Maestro, M., Ricci, A., Dechordi, S. R., Marzi, S., Millimaggi, D. F., & Galzio, R. J. (2016). Dural repair using autologous fat: Our experience and review of the literature. Surgical neurology international, 7S463-8. https://doi.org/10.4103/2152-7806.185777
Di Vitantonio, Hambra, et al. "Dural repair using autologous fat: Our experience and review of the literature." Surgical neurology international vol. 7 (2016): S463-8. doi: https://doi.org/10.4103/2152-7806.185777
Di Vitantonio H, De Paulis D, Del Maestro M, Ricci A, Dechordi SR, Marzi S, Millimaggi DF, Galzio RJ. Dural repair using autologous fat: Our experience and review of the literature. Surg Neurol Int. 2016 Jul 07;7:S463-8. doi: 10.4103/2152-7806.185777. eCollection 2016. PMID: 27500007; PMCID: PMC4960926.
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Surg Neurol Int. 2016 Jul 07;7:S463-8. doi: 10.4103/2152-7806.185777. eCollection 2016.

Dural repair using autologous fat: Our experience and review of the literature.

Surgical neurology international

Hambra Di Vitantonio, Danilo De Paulis, Mattia Del Maestro, Alessandro Ricci, Soheila Raysi Dechordi, Sara Marzi, Daniele F Millimaggi, Renato J Galzio

Affiliations

  1. Department of Life, Health and Environmental Sciences (MESVA), University of L'Aquila, L'Aquila, Italy.
  2. Department of Neurosurgery, San Salvatore City Hospital, L'Aquila, Italy.

PMID: 27500007 PMCID: PMC4960926 DOI: 10.4103/2152-7806.185777

Abstract

BACKGROUND: Various materials have been proposed to obliterate dead spaces and to reconstruct dural defects during a neurosurgical approach. This study describes our technique of using the abdominal autologous fat graft and evaluates the complications and characteristics related to the use of this tissue during cranial procedures.

METHODS: Autologous fat grafts were used in 296 patients with basicranial and convexity extraaxial tumors from April 2005 to January 2015. The adipose tissue was removed from the paraumbilical abdominal region and was transformed into a thin foil. When possible, a watertight suture was made between the dural or bone edge with a fat graft. We always used fibrin glue to reinforce the dural closure.

RESULTS: Complications occurred between 2 days and 1 year following procedure. Cerebrospinal fluid leaks were found in 11 cases. No case of mortality, pseudomeningoceles, fistula, infections, bacterial meningitides, or lipoid meningitides was reported. No patient required removal of the graft. No adhesion was observed between the brain and the autologous fat. Other fat-related complications observed were 2 cases of fat necrosis in the abdomen and 2 cases of abdominal hemorrhage.

CONCLUSION: The technique of harvesting and applying fat grafts is fairly simple, although it must be performed meticulously to be effective. Our experience has led us to believe that the use of fat grafts presents low morbidity and mortality. However, a neurosurgeon should never forget the possible late or early complications related to the use of fat grafts.

Keywords: Autologous fat graft; dural repair; dural substitute; watertight suture

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