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Khan MT, Oghlakian R, Koubeissi MZ. Unusual atypical language lateralization. Epilepsy Behav Case Rep. 2016;6:73-4doi: 10.1016/j.ebcr.2016.01.007.
Khan, M. T., Oghlakian, R., & Koubeissi, M. Z. (2016). Unusual atypical language lateralization. Epilepsy & behavior case reports, 673-4. https://doi.org/10.1016/j.ebcr.2016.01.007
Khan, Muhammad T, et al. "Unusual atypical language lateralization." Epilepsy & behavior case reports vol. 6 (2016): 73-4. doi: https://doi.org/10.1016/j.ebcr.2016.01.007
Khan MT, Oghlakian R, Koubeissi MZ. Unusual atypical language lateralization. Epilepsy Behav Case Rep. 2016 Mar 09;6:73-4. doi: 10.1016/j.ebcr.2016.01.007. eCollection 2016. PMID: 27668182; PMCID: PMC5024312.
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Epilepsy Behav Case Rep. 2016 Mar 09;6:73-4. doi: 10.1016/j.ebcr.2016.01.007. eCollection 2016.

Unusual atypical language lateralization.

Epilepsy & behavior case reports

Muhammad T Khan, Roger Oghlakian, Mohamad Z Koubeissi

Affiliations

  1. West Virginia University, Department of Neurology, 1 Medical Center Drive, Morgantown, WV 26506, United States.

PMID: 27668182 PMCID: PMC5024312 DOI: 10.1016/j.ebcr.2016.01.007

Abstract

Determining the language-dominant hemisphere is essential for planning epilepsy surgery. A 60-year-old right-handed woman with epilepsy since age 16 failed a partial right anterior lobectomy at age 21. Later, a brain MRI found extensive right-sided cortical dysplasia and periventricular heterotopia. Subsequently, prolonged video-EEG monitoring localized her seizures to the right temporoparietal region. Functional MRI was inconclusive in lateralizing her language, prompting a Wada test, which strongly lateralized language to the right. This unique case of atypical language representation in a right-handed individual with an extensive right-hemispheric congenital malformation and seizure focus illustrates the important thorough presurgical language assessment.

References

  1. Epileptic Disord. 2007 Jun;9(2):111-26 - PubMed
  2. Epilepsia. 2009 Jun;50(6):1505-16 - PubMed

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