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Elife. 2016 Sep 26;5. doi: 10.7554/eLife.17047.

Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling.

eLife

Alessia Calcagnì, Lotte Kors, Eric Verschuren, Rossella De Cegli, Nicolina Zampelli, Edoardo Nusco, Stefano Confalonieri, Giovanni Bertalot, Salvatore Pece, Carmine Settembre, Gabriel G Malouf, Jaklien C Leemans, Emile de Heer, Marco Salvatore, Dorien Jm Peters, Pier Paolo Di Fiore, Andrea Ballabio

Affiliations

  1. Telethon Institute of Genetics and Medicine, TIGEM, Pozzuoli, Naples, Italy.
  2. Department of Pathology, Academical Medical Center, Amsterdam, The Netherlands.
  3. Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
  4. Department of Human Genetics, Leiden University Medical Center, Leiden, Netherlands.
  5. Molecular Medicine Program, European Institute of Oncology, Milan, Italy.
  6. IFOM, The FIRC Institute for Molecular Oncology Foundation, Milan, Italy.
  7. Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.
  8. Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.
  9. Jan and Dan Duncan Neurological Research Institute, Texas Children Hospital, Houston, United States.
  10. Medical Genetics, Federico II University, Naples, Italy.
  11. Medical Genetics, Department of Medical and Translational Sciences, Federico II University, Naples, Italy.
  12. Department of Medical Oncology Groupe Hospitalier Pitie-Salpetriere, University Paris 6, Paris, France.
  13. Assistance Publique Hopitaux de Paris, University Paris 6, Paris, France.
  14. Faculty of Medicine Pierre et Marie Curie, University Paris 6, Paris, France.
  15. Institut Universitaire de Cancerologie GRC5, University Paris 6, Paris, France.
  16. IRCCS-SDN, Naples, Italy.

PMID: 27668431 PMCID: PMC5036965 DOI: 10.7554/eLife.17047

[No abstract available.]

Keywords: TFEB; WNT pathway; cancer biology; human biology; medicine; mouse; renal cell carcinoma

Conflict of interest statement

The authors declare that no competing interests exist.

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