Open Access Maced J Med Sci. 2016 Sep 15;4(3):523-525. doi: 10.3889/oamjms.2016.087. Epub 2016 Aug 24.

Venous Thromboembolism - Current Diagnostic and Treatment Modalities.

Open access Macedonian journal of medical sciences

Marijan Bosevski, Elizabeta Srbinovska-Kostovska

PMID: 27703586 PMCID: PMC5042646 DOI: 10.3889/oamjms.2016.087

Abstract

BACKGROUND: Pulmonary embolism and deep venous thrombosis, known as venous thromboembolism (VTE), are associated with a high proportion of morbidity and mortality.

AIM: Aim of this review is to emphasise current diagnostic and therapeutic modalities for VTE.

RESULTS: No differences have been noticed in European and American guidelines in diagnostic approach of this disorder. Today there is enough clinical information for the use of heparin (either, unfractionated or low molecular) and vitamin K antagonists in the treatment of acute and chronic phases of VTE. Novel oral anticoagulants seem to have some advantages in the treatment of this disorder. Rivaroxaban has been approved widespread, for use as a single-drug approach of VTE.

CONCLUSION: Both guidelines are almost similar and good basis for evidence-based treatment of this disorder.

Keywords: deep venous thrombosis treatment; novel oral anticoagulants; pulmonary embolism; venous thromboembolism

References

1. J Am Coll Cardiol. 2016 Jan 19;67(2):162-70 - PubMed
2. Rev Esp Cardiol. 2010 Apr;63(4):451-71 - PubMed
3. Vasc Health Risk Manag. 2016 Feb 10;12 :23-34 - PubMed
4. Rev Esp Cardiol (Engl Ed). 2015 Jan;68(1):10-6 - PubMed
5. Chest. 2016 Feb;149(2):315-52 - PubMed
6. Presse Med. 2015 Dec;44(12 Pt 2):e377-83 - PubMed
7. Ann Pharmacother. 2015 Aug;49(8):869-75 - PubMed

Publication Types

• Review
• Journal Article