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Case Rep Nephrol. 2016;2016:4260365. doi: 10.1155/2016/4260365. Epub 2016 Sep 14.

Interstitial Nephritis in a Patient with Inflammatory Bowel Disease.

Case reports in nephrology

Payaswini Vasanth, Michelle Parmley, Jose Torrealba, Tamim Hamdi

Affiliations

  1. Department of Internal Medicine, Division of Nephrology, UT Southwestern Medical Center, Dallas, TX, USA.
  2. Department of Pathology, UT Southwestern Medical Center, Dallas, TX, USA.

PMID: 27703822 PMCID: PMC5039298 DOI: 10.1155/2016/4260365

Abstract

Tubulointerstitial nephritis in patients with inflammatory bowel disease has been linked to the use of 5-ASA derivatives. Various aspects of this theory have been challenged with a potential role for the underlying autoimmune disorder. Steroids are the mainstay of treatment and mycophenolate mofetil might be an effective alternative. We report a patient who responded well to mycophenolate despite continuing mesalamine, the suspected offending agent.

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