Display options
Cite
Hong F, Blonquist TM, Halpenny B, et al. Patient-reported symptom distress, and most bothersome issues, before and during cancer treatment. Patient Relat Outcome Meas. 2016;7:127-35doi: 10.2147/PROM.S95593.
Hong, F., Blonquist, T. M., Halpenny, B., & Berry, D. L. (2016). Patient-reported symptom distress, and most bothersome issues, before and during cancer treatment. Patient related outcome measures, 7127-35. https://doi.org/10.2147/PROM.S95593
Hong, Fangxin, et al. "Patient-reported symptom distress, and most bothersome issues, before and during cancer treatment." Patient related outcome measures vol. 7 (2016): 127-35. doi: https://doi.org/10.2147/PROM.S95593
Hong F, Blonquist TM, Halpenny B, Berry DL. Patient-reported symptom distress, and most bothersome issues, before and during cancer treatment. Patient Relat Outcome Meas. 2016 Sep 12;7:127-35. doi: 10.2147/PROM.S95593. eCollection 2016. PMID: 27672346; PMCID: PMC5026183.
Copy Download .nbib Format: NLM
Share it on

Patient Relat Outcome Meas. 2016 Sep 12;7:127-35. doi: 10.2147/PROM.S95593. eCollection 2016.

Patient-reported symptom distress, and most bothersome issues, before and during cancer treatment.

Patient related outcome measures

Fangxin Hong, Traci M Blonquist, Barbara Halpenny, Donna L Berry

Affiliations

  1. Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Biostatistics, Harvard School of Public Health, Boston, MA, USA.
  2. Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  3. Department of Nursing and Patient Care Services, The Phyllis F. Cantor Center, Dana-Farber Cancer Institute, Boston, MA, USA.
  4. Department of Nursing and Patient Care Services, The Phyllis F. Cantor Center, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA, USA.

PMID: 27672346 PMCID: PMC5026183 DOI: 10.2147/PROM.S95593

Abstract

INTRODUCTION: Frequently reported symptoms and treatment side effects may not be the most bothersome issues to patients with cancer. The purpose of this study was to investigate patient-reported symptom distress and bothersome issues among participants with cancer.

METHODS: Participants completed the Symptom Distress Scale-15 before treatment (T1) and during cancer treatment (T2) and reported up to two most bothersome issues among symptoms rated with moderate-to-severe distress. We compared symptom ratings and perceived bother and explored two approaches predicting patients' most bothersome issues: worst absolute symptom score or worst change from pretreatment.

RESULTS: Significantly, (P≤0.0002) more patients reported moderate-to-severe distress at T2 for eight of 13 symptoms. At T1, 81% of patients reported one and 56% reported multiple symptoms with moderate-to-severe distress, while at T2, 89% reported one and 69% reported multiple symptoms with moderate-to-severe distress. Impact on sexual activity/interest, pain, fatigue, and insomnia were the most prevalent symptoms with moderate-to-severe distress. Fatigue, pain, and insomnia were perceived most often as bothersome. When one symptom was rated moderate-to-severe, predictive accuracy of the absolute score was 46% and 48% (T1 & T2) and 38% with the change score (T2-T1). When two or more symptoms were rated moderate-to-severe, predictive accuracy of the absolute score was 76% and 79% (T1 & T2) and 70% with the change score (T2-T1).

CONCLUSION: More patients experienced moderate-to-severe symptom distress after treatment initiation. Patient identification of bothersome issues could not be assumed based on prevalence of symptoms reported with moderate-to-severe distress. The absolute symptom distress scores identified patients' most bothersome issues with good accuracy, outperforming change scores.

Keywords: SDS-15; most bothersome issues; perceived bother; prediction; symptom distress

References

  1. Cancer Nurs. 2015 Jan-Feb;38(1):E29-54 - PubMed
  2. Urol Oncol. 2013 Nov;31(8):1504-10 - PubMed
  3. Eur J Oncol Nurs. 2010 Dec;14(5):400-9 - PubMed
  4. Cancer. 2000 Oct 1;89(7):1634-46 - PubMed
  5. Health Psychol. 2014 Mar;33(3):222-31 - PubMed
  6. Cancer Nurs. 2014 Mar-Apr;37(2):E51-9 - PubMed
  7. Patient Educ Couns. 2007 Feb;65(2):223-9 - PubMed
  8. J Natl Compr Canc Netw. 2012 Feb;10(2):149-57 - PubMed
  9. J Clin Oncol. 2014 Jan 20;32(3):199-205 - PubMed
  10. Urology. 2000 Dec 20;56(6):899-905 - PubMed
  11. Cancer Nurs. 2013 Jul-Aug;36(4):292-300 - PubMed
  12. Support Care Cancer. 2009 Dec;17(12):1493-7 - PubMed
  13. J Clin Oncol. 2011 Mar 20;29(9):1216-20 - PubMed
  14. J Pain Symptom Manage. 2007 Jul;34(1):94-104 - PubMed
  15. J Natl Cancer Inst Monogr. 2007;(37):16-21 - PubMed
  16. Psychooncology. 2001 Jan-Feb;10(1):19-28 - PubMed
  17. Oncol Nurs Forum. 2011 May;38(3):369-75 - PubMed
  18. J Geriatr Oncol. 2013 Jan;4(1):71-7 - PubMed
  19. Cancer Nurs. 1978 Oct;1(5):373-8 - PubMed
  20. Cancer. 2013 Dec 15;119(24):4333-40 - PubMed
  21. J Pain Symptom Manage. 2009 Apr;37(4):715-36 - PubMed
  22. J Clin Oncol. 2002 Jan 15;20(2):557-66 - PubMed
  23. Cancer Invest. 2003 Jun;21(3):374-81 - PubMed
  24. BMC Cancer. 2013 Apr 23;13:201 - PubMed
  25. J Clin Oncol. 2005 May 20;23(15):3552-61 - PubMed

Publication Types

Grant support