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Int J Surg Case Rep. 2016;28:38-41. doi: 10.1016/j.ijscr.2016.09.011. Epub 2016 Sep 21.

Combined liver transplantation and sleeve gastrectomy for end-stage liver disease in a bariatric patient: First European case-report.

International journal of surgery case reports

Laura Tariciotti, Stefano D'Ugo, Tommaso Maria Manzia, Valeria Tognoni, Giuseppe Sica, Paolo Gentileschi, Giuseppe Tisone

Affiliations

  1. Liver and Kidney Transplant Centre, Fondazione Policlinico "Tor Vergata", University of Rome "Tor Vergata", Viale Oxford 81, 00133 Rome, Italy. Electronic address: [email protected].
  2. General Surgery and Bariatric Surgery Unit, Fondazione Policlinico "Tor Vergata", University of Rome "Tor Vergata", Viale Oxford 81, 00133 Rome, Italy.
  3. Liver and Kidney Transplant Centre, Fondazione Policlinico "Tor Vergata", University of Rome "Tor Vergata", Viale Oxford 81, 00133 Rome, Italy.

PMID: 27677115 PMCID: PMC5037123 DOI: 10.1016/j.ijscr.2016.09.011

Abstract

INTRODUCTION: Obesity is a contributor to the global burden of chronic diseases, including non-alcoholic fatty liver disease and non-alcoholic steatohepatitis (NASH). NASH cirrhosis is becoming a leading indication for liver transplant (LT). Obese transplanted patients have higher morbidity and mortality rates. One strategy, to improve the outcomes in these patients, includes bariatric surgery at the time of LT. Herein we report the first European combined LT and sleeve gastrectomy (SG).

CASE PRESENTATION: A 53 years old woman with Hepatocellular carcinoma and Hepatitis C virus related cirrhosis, was referred to our unit. She also presented with severe morbid obesity (BMI 40kg/m

CONCLUSION: Despite the ideal approach to the management of the obese LT patients remains unknown, we strongly support the combined procedure during LT in selected patients, offering advantages in terms of allograft and patient survival, maintenance of weigh loss that will ultimately reduce obese related co-morbidities.

Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

Keywords: Bariatric surgery; Case report; Liver transplantation; Non-alcoholic steatohepatitis cirrhosis; Obesity; Sleeve gastrectomy

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