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Obstet Med. 2013 Sep;6(3):138-140. doi: 10.1258/om.2012.120030. Epub 2013 Jul 23.

Severe metabolic alkalosis in pregnancy.

Obstetric medicine

Charlotte Frise, Muna Noori, Catherine Williamson

Affiliations

  1. John Radcliffe Hospital, Oxford University Hospitals NHS Trust.
  2. Queen Charlotte's and Chelsea Hospital, Imperial College Healthcare NHS Trust.
  3. Queen Charlotte's and Chelsea Hospital, Imperial College London, London , UK.

PMID: 27708709 PMCID: PMC5032930 DOI: 10.1258/om.2012.120030

Abstract

Metabolic alkalosis is uncommon in pregnancy and is most often the result of severe vomiting. If this is present at the time of delivery, transient metabolic derangement in the fetus can occur, potentially requiring additional organ support. A 22-year-old woman is described, who presented at 37 weeks gestation with a severe metabolic alkalosis, vomiting and acute renal and hepatic impairment. The investigations, management options and maternal and fetal outcome are described.

Keywords: gastroenterology; high-risk pregnancy; maternal–fetal medicine; metabolism

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