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Medepalli K, Lee CM, Benninger LA, et al. Psychosis: call a surgeon? A rare etiology of psychosis requiring resection. SAGE Open Med Case Rep. 2016;4:2050313X16670084doi: 10.1177/2050313X16670084.
Medepalli, K., Lee, C. M., Benninger, L. A., & Elwing, J. M. (2016). Psychosis: call a surgeon? A rare etiology of psychosis requiring resection. SAGE open medical case reports, 42050313X16670084. https://doi.org/10.1177/2050313X16670084
Medepalli, Kantha, et al. "Psychosis: call a surgeon? A rare etiology of psychosis requiring resection." SAGE open medical case reports vol. 4 (2016): 2050313X16670084. doi: https://doi.org/10.1177/2050313X16670084
Medepalli K, Lee CM, Benninger LA, Elwing JM. Psychosis: call a surgeon? A rare etiology of psychosis requiring resection. SAGE Open Med Case Rep. 2016 Sep 21;4:2050313X16670084. doi: 10.1177/2050313X16670084. eCollection 2016. PMID: 27708781; PMCID: PMC5034462.
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SAGE Open Med Case Rep. 2016 Sep 21;4:2050313X16670084. doi: 10.1177/2050313X16670084. eCollection 2016.

Psychosis: call a surgeon? A rare etiology of psychosis requiring resection.

SAGE open medical case reports

Kantha Medepalli, Cody M Lee, Lauryn A Benninger, Jean M Elwing

Affiliations

  1. Department of Internal Medicine, University of Cincinnati Medical Center, Cincinnati, OH, USA.
  2. Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of Cincinnati Medical Center, Cincinnati, OH, USA.

PMID: 27708781 PMCID: PMC5034462 DOI: 10.1177/2050313X16670084

Abstract

OBJECTIVE: Anti-N-methyl-d-aspartate receptor encephalitis is a rare but emerging cause of autoimmune encephalitis. Our objective is to present a case of this rare disease while highlighting the importance of an aggressive search for underlying malignancy as well as the common mischaracterization of primary psychiatric illness that occurs in these patients.

METHODS: A young Caucasian female with no known psychiatric history presented with acute onset of seizures and psychosis.

RESULTS: Magnetic resonance imaging abdomen and pelvis showed a 6-mm ovarian teratoma which was not visualized on initial computed tomographic scans. Pathology was consistent with a mature teratoma. Both serum and cerebrospinal fluid N-methyl-

CONCLUSION: An exhaustive search for underlying malignancy and specifically ovarian teratoma in young women should be completed in these patients. Diagnosis often is delayed given the prominent psychiatric manifestations and providers should be aware and strongly consider this in younger women with acute onset of neuropsychiatric symptoms.

Keywords: Anti–N-methyl-d-aspartate receptor; autoimmune encephalitis; psychosis; teratoma

Conflict of interest statement

The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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