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Respir Med Case Rep. 2016 Sep 16;19:128-131. doi: 10.1016/j.rmcr.2016.09.003. eCollection 2016.

Löffler syndrome on a Louisiana pig farm.

Respiratory medicine case reports

Kevin Gipson, Ryan Avery, Heena Shah, Derek Pepiak, Rodolfo E Bégué, John Malone, Luke A Wall

Affiliations

  1. Division of Pediatric Pulmonology, Department of Pediatrics, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  2. Louisiana State University School of Veterinary Medicine, Department of Pathobiological Sciences, Baton Rouge, LA, USA.
  3. Section of Allergy Immunology, Department of Pediatrics, Louisiana State University Health Sciences Center and Children's Hospital New Orleans, New Orleans, LA, USA.
  4. Division of Pediatric Pulmonology, Department of Pediatrics, Ochsner for Children and the University of Queensland School of Medicine, New Orleans, LA, USA.
  5. Section of Infectious Diseases, Department of Pediatrics, Louisiana State University Health Sciences Center and Children's Hospital New Orleans, New Orleans, LA, USA.

PMID: 27709064 PMCID: PMC5043414 DOI: 10.1016/j.rmcr.2016.09.003

Abstract

Löffler syndrome, a fulminant eosinophilic pneumonitis associated with the larval migratory phase of human parasites, is rarely reported in the United States. A previously healthy 8-year-old male was hospitalized with tachypnea, cough, hypoxemia, and fever of one week's duration. History revealed exposure to pigs on his family's farm in southernmost Louisiana, where the patient was responsible for cleaning the farm's pigpens. His fingernails were soiled and extremely short, with the edge of the nail bed exposed secondary to onychophagia. Laboratory evaluation demonstrated peripheral eosinophilia (39%), pulmonary eosinophilia (86%), high total IgE, diffuse reticulonodular lung opacities, and mixed obstructive and restrictive pulmonary function pattern. Systemic corticosteroids were initiated for his acute respiratory insufficiency and produced rapid clinical improvement. Serum

Keywords: Ascaris suum; BAL, Broncho-alveolar lavage; ED, emergency department; FEF, forced expiratory flow; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; LPM, liter per minute; LSU, Louisiana State University; Loffler syndrome; Onychophagia; Pediatric pulmonology; Pulmonary eosinophilia; RV, residual volume; TLC, total lung capacity

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