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Pharmaceuticals (Basel). 2010 Mar 02;3(3):448-470. doi: 10.3390/ph3030448.

Cell-Penetrating Peptides for Antiviral Drug Development.

Pharmaceuticals (Basel, Switzerland)

Melaine Delcroix, Lee W Riley

Affiliations

  1. School of Public Health, University of California, Berkeley, CA 94720, USA. [email protected].
  2. School of Public Health, University of California, Berkeley, CA 94720, USA. [email protected].

PMID: 27713263 PMCID: PMC4033964 DOI: 10.3390/ph3030448

Abstract

Viral diseases affect hundreds of millions of people worldwide, and the few available drugs to treat these diseases often come with limitations. The key obstacle to the development of new antiviral agents is their delivery into infected cells

Keywords: antisense; antivirals; cell-penetrating peptide; drug delivery

References

  1. Cell. 2008 Aug 22;134(4):577-86 - PubMed
  2. Virology. 2007 Jun 20;363(1):91-103 - PubMed
  3. Anal Biochem. 2006 Jun 1;353(1):7-14 - PubMed
  4. Indian J Med Res. 2009 Sep;130(3):296-310 - PubMed
  5. Intervirology. 2009;52(3):135-40 - PubMed
  6. J Exp Med. 2008 Jan 21;205(1):7-12 - PubMed
  7. J Neurosci. 2002 Jul 1;22(13):5423-31 - PubMed
  8. Bioconjug Chem. 2005 Jul-Aug;16(4):959-66 - PubMed
  9. Nucleic Acids Res. 2005 Aug 02;33(13):4345-56 - PubMed
  10. J Biol Chem. 2003 Jul 4;278(27):24388-98 - PubMed
  11. J Virol. 2006 Dec;80(23):11510-9 - PubMed
  12. Antimicrob Agents Chemother. 2006 Mar;50(3):984-93 - PubMed
  13. Trends Pharmacol Sci. 2009 Jul;30(7):341-5 - PubMed
  14. Bioconjug Chem. 2007 Jan-Feb;18(1):50-60 - PubMed
  15. J Biol Chem. 1994 Apr 8;269(14):10444-50 - PubMed
  16. Trends Cell Biol. 2000 Jul;10(7):290-5 - PubMed
  17. Proc Natl Acad Sci U S A. 1978 Jan;75(1):280-4 - PubMed
  18. Virus Res. 2009 Mar;140(1-2):49-56 - PubMed
  19. J Investig Dermatol Symp Proc. 2003 Oct;8(2):207-11 - PubMed
  20. Nat Rev Microbiol. 2004 Sep;2(9):704-20 - PubMed
  21. Adv Drug Deliv Rev. 2007 Mar 30;59(2-3):134-40 - PubMed
  22. J Biol Chem. 2002 Sep 27;277(39):36018-23 - PubMed
  23. FASEB J. 1998 Jan;12(1):67-77 - PubMed
  24. Nat Rev Drug Discov. 2007 Dec;6(12):1001-18 - PubMed
  25. Antiviral Res. 2007 Jan;73(1):12-23 - PubMed
  26. J Neurosci. 1996 Jan;16(1):253-61 - PubMed
  27. Trends Biotechnol. 1993 Sep;11(9):384-6 - PubMed
  28. Proc Natl Acad Sci U S A. 1978 Jan;75(1):285-8 - PubMed
  29. J Gen Virol. 2005 Nov;86(Pt 11):3081-90 - PubMed
  30. J Virol. 2005 Apr;79(8):4599-609 - PubMed
  31. Biochem J. 2002 Nov 1;367(Pt 3):761-9 - PubMed
  32. Biochem Soc Trans. 2007 Aug;35(Pt 4):770-4 - PubMed
  33. Nucleic Acids Res. 1997 Jul 15;25(14):2730-6 - PubMed
  34. J Virol. 2007 Jun;81(11):5637-48 - PubMed
  35. Cancer Res. 2002 Apr 1;62(7):2013-8 - PubMed
  36. Nucleic Acids Res. 2008 Nov;36(20):6343-54 - PubMed
  37. Mol Ther. 2008 Jun;16(6):1120-8 - PubMed
  38. J Biol Chem. 2004 Mar 5;279(10):9208-14 - PubMed
  39. Virology. 2008 Jul 5;376(2):357-70 - PubMed
  40. Proc Natl Acad Sci U S A. 1994 Jan 18;91(2):664-8 - PubMed
  41. J Biol Chem. 1997 Jun 20;272(25):16010-7 - PubMed
  42. Science. 1993 Sep 10;261(5127):1454-7 - PubMed
  43. Nat Biotechnol. 2001 Apr;19(4):360-4 - PubMed
  44. Science. 1999 Sep 3;285(5433):1569-72 - PubMed
  45. Nat Biotechnol. 1998 May;16(5):440-3 - PubMed
  46. Nat Med. 1999 Jan;5(1):29-33 - PubMed
  47. Bioorg Med Chem Lett. 2004 Nov 15;14(22):5595-8 - PubMed
  48. Hepatology. 2002 Nov;36(5 Suppl 1):S135-44 - PubMed
  49. Nat Biotechnol. 2000 Apr;18(4):410-4 - PubMed
  50. Adv Drug Deliv Rev. 2005 Feb 28;57(4):637-51 - PubMed
  51. Bioconjug Chem. 2004 Mar-Apr;15(2):290-9 - PubMed
  52. Antimicrob Agents Chemother. 2006 Nov;50(11):3724-33 - PubMed
  53. Antimicrob Agents Chemother. 2007 Jul;51(7):2470-82 - PubMed
  54. Proc Natl Acad Sci U S A. 2004 Jun 15;101(24):9073-8 - PubMed
  55. Mol Ther. 2004 Apr;9(4):596-606 - PubMed
  56. Nat Biotechnol. 1998 Sep;16(9):857-61 - PubMed
  57. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8786-91 - PubMed
  58. Oligonucleotides. 2008 Sep;18(3):277-86 - PubMed
  59. Vet Microbiol. 2006 Oct 31;117(2-4):117-29 - PubMed
  60. Cell. 1997 Jan 24;88(2):223-33 - PubMed
  61. Circ Res. 2007 Jun 8;100(11):1626-33 - PubMed
  62. Oligonucleotides. 2008 Dec;18(4):329-35 - PubMed
  63. Trends Microbiol. 2002;10(10 Suppl):S8-14 - PubMed
  64. Arch Virol. 2008;153(7):1291-8 - PubMed
  65. Antimicrob Agents Chemother. 2007 May;51(5):1596-607 - PubMed
  66. J Virol. 2001 Mar;75(6):2634-45 - PubMed
  67. Molecules. 2009 Mar 25;14(3):1304-23 - PubMed
  68. Virology. 2006 Jan 20;344(2):439-52 - PubMed
  69. Nat Rev Immunol. 2006 Jun;6(6):447-56 - PubMed
  70. Nucleic Acids Res. 2005 Nov 30;33(21):6837-49 - PubMed
  71. Adv Drug Deliv Rev. 2004 Apr 23;56(7):931-46 - PubMed
  72. Methods Enzymol. 2005;391:351-73 - PubMed
  73. Biochem J. 2006 Oct 1;399(1):1-7 - PubMed
  74. Antiviral Res. 2008 Aug;79(2):136-41 - PubMed
  75. J Virol. 2004 Jun;78(11):5891-9 - PubMed
  76. Mol Cancer Ther. 2008 Mar;7(3):712-20 - PubMed
  77. Antiviral Res. 2009 Jun;82(3):122-33 - PubMed
  78. Antimicrob Agents Chemother. 2009 May;53(5):2089-99 - PubMed
  79. Proc Natl Acad Sci U S A. 2005 May 17;102(20):7103-8 - PubMed
  80. Arch Virol. 2008;153(5):929-37 - PubMed
  81. Annu Rev Med. 2004;55:355-72 - PubMed
  82. Virology. 2005 Jan 20;331(2):418-28 - PubMed
  83. Exp Parasitol. 2008 Mar;118(3):303-7 - PubMed
  84. Adv Drug Deliv Rev. 2008 Mar 1;60(4-5):517-29 - PubMed
  85. Am J Vet Res. 2008 Jan;69(1):23-32 - PubMed
  86. PLoS Pathog. 2009 Oct;5(10):e1000557 - PubMed
  87. J Virol. 2002 Apr;76(8):3881-91 - PubMed
  88. Vaccine. 2009 Aug 13;27(37):5142-51 - PubMed
  89. J Control Release. 2006 Dec 1;116(3):304-13 - PubMed
  90. Oligonucleotides. 2008 Spring;18(1):9-20 - PubMed
  91. J Antimicrob Chemother. 2008 Sep;62(3):555-65 - PubMed
  92. Curr Top Med Chem. 2007;7(7):651-60 - PubMed
  93. N Engl J Med. 2009 Dec 3;361(23):2209-20 - PubMed
  94. Bioconjug Chem. 2007 Jul-Aug;18(4):1325-31 - PubMed
  95. Cell. 1988 Dec 23;55(6):1189-93 - PubMed
  96. Mol Ther. 2008 Sep;16(9):1624-9 - PubMed
  97. Biochim Biophys Acta. 1998 Nov 11;1414(1-2):127-39 - PubMed
  98. PLoS Pathog. 2006 Jan;2(1):e1 - PubMed
  99. J Virol. 2005 Aug;79(15):9665-76 - PubMed
  100. Curr Pharm Des. 2008;14(25):2619-34 - PubMed
  101. Antiviral Res. 2009 Nov;84(2):142-9 - PubMed
  102. Nat Med. 2000 Nov;6(11):1253-7 - PubMed
  103. J Gen Virol. 2008 Apr;89(Pt 4):939-48 - PubMed
  104. J Virol. 2007 Nov;81(21):11669-80 - PubMed
  105. Antimicrob Agents Chemother. 2008 Jun;52(6):1970-81 - PubMed
  106. FEMS Microbiol Lett. 2002 Oct 8;215(2):267-72 - PubMed
  107. PLoS Med. 2006 Jul;3(7):e242 - PubMed
  108. Antiviral Res. 2009 Nov;84(2):131-41 - PubMed

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