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Szczepanik AM, Paszko A, Szura M, et al. Alternative staging of regional lymph nodes in gastric cancer. Prz Gastroenterol. 2016;11(3):145-149doi: 10.5114/pg.2016.61492.
Szczepanik, A. M., Paszko, A., Szura, M., Scully-Horner, T., & Kulig, J. (2016). Alternative staging of regional lymph nodes in gastric cancer. Przeglad gastroenterologiczny, 11(3), 145-149. https://doi.org/10.5114/pg.2016.61492
Szczepanik, Antoni M, et al. "Alternative staging of regional lymph nodes in gastric cancer." Przeglad gastroenterologiczny vol. 11,3 (2016): 145-149. doi: https://doi.org/10.5114/pg.2016.61492
Szczepanik AM, Paszko A, Szura M, Scully-Horner T, Kulig J. Alternative staging of regional lymph nodes in gastric cancer. Prz Gastroenterol. 2016;11(3):145-149. doi: 10.5114/pg.2016.61492. Epub 2016 Jul 27. PMID: 27713774; PMCID: PMC5047974.
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Prz Gastroenterol. 2016;11(3):145-149. doi: 10.5114/pg.2016.61492. Epub 2016 Jul 27.

Alternative staging of regional lymph nodes in gastric cancer.

Przeglad gastroenterologiczny

Antoni M Szczepanik, Agata Paszko, Miroslaw Szura, Thecla Scully-Horner, Jan Kulig

Affiliations

  1. 1 Department of General, Gastrointestinal, and Oncologic Surgery, Jagiellonian University Medical College, Krakow, Poland.
  2. Intensive Care Unit, Queen Alexandra Hospital, Portsmouth, United Kingdom.

PMID: 27713774 PMCID: PMC5047974 DOI: 10.5114/pg.2016.61492

Abstract

The TNM pN stage based on the number of metastatic lymph nodes is an independent prognostic factor in gastric cancer. Many studies have highlighted the phenomenon of stage migration and problems in comparing groups of patients with different numbers of total lymph nodes harvested within TNM staging. The current version of UICC/AJCC and JGCA TNM classifications postulates a minimal number of 16 lymph nodes as the base for N stage determination. Alternative systems such as lymph node ratio (LNR), positive to negative lymph node ratio (PNLNR), and LOGODDS (or LODDS), were implemented to increase the quality of LN assessment. These methods have reached the background in the literature, but to date no standard approach according to the cut-offs for the stages has been implemented. LOGODDS is the method that most reflects the number of harvested lymph nodes. The rationale for alternative staging methods, their correlations, and limitations are presented.

Keywords: gastric cancer; lymph node staging; lymphadenectomy

Conflict of interest statement

The authors declare no conflict of interest.

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