Display options
Cite
Kawali A, Jose RT, Aishwarya, et al. Personality and uveitis. J Ophthalmic Inflamm Infect. 2016;6(1):36doi: 10.1186/s12348-016-0108-x.
Kawali, A., Jose, R. T., Aishwarya, Kurian, M., Kacha, K., Mahendradas, P., & Shetty, R. (2016). Personality and uveitis. Journal of ophthalmic inflammation and infection, 6(1), 36. https://doi.org/10.1186/s12348-016-0108-x
Kawali, Ankush, et al. "Personality and uveitis." Journal of ophthalmic inflammation and infection vol. 6,1 (2016): 36. doi: https://doi.org/10.1186/s12348-016-0108-x
Kawali A, Jose RT, Aishwarya, Kurian M, Kacha K, Mahendradas P, Shetty R. Personality and uveitis. J Ophthalmic Inflamm Infect. 2016 Dec;6(1):36. doi: 10.1186/s12348-016-0108-x. Epub 2016 Oct 06. PMID: 27714662; PMCID: PMC5053967.
Copy Download .nbib Format: NLM
Share it on

J Ophthalmic Inflamm Infect. 2016 Dec;6(1):36. doi: 10.1186/s12348-016-0108-x. Epub 2016 Oct 06.

Personality and uveitis.

Journal of ophthalmic inflammation and infection

Ankush Kawali, Ringhoo Theresa Jose, Aishwarya, Mathew Kurian, Kushal Kacha, Padmamalini Mahendradas, Rohit Shetty

Affiliations

  1. Uveitis and Ocular Immunology Department, Narayana Nethralaya, Bangalore, India. [email protected].
  2. Narayana Nethralaya, 121/C, Chord road, 1st 'R'Block, Rajajinagar, Bangalore, 60010, India. [email protected].
  3. Narayana Nethralaya, 121/C, Chord road, 1st 'R'Block, Rajajinagar, Bangalore, 60010, India.
  4. General Ophthalmology Department, Narayana Nethralaya, Bangalore, India.
  5. Uveitis and Ocular Immunology Department, Narayana Nethralaya, Bangalore, India.
  6. Cataract and Refractive Department, Narayana Nethralaya, Bangalore, India.

PMID: 27714662 PMCID: PMC5053967 DOI: 10.1186/s12348-016-0108-x

Abstract

BACKGROUND: Psycho-immunology is an emerging branch of science which studies the interaction between the brain and the immune system. The purpose of this study is to identify the types of personality factors in patients with non-infectious uveitis and to find its association with a particular uveitic entity if any. This is a prospective, observational, case-control study of 186 patients with non-infectious uveitis (group A) and controls from general ophthalmology outpatient department (group B). "Global 5/SLOAN" personality questionnaire was used which is based on the five-factor theory of personality which describes personality factors based on the presence or absence of five primary dimensions, viz extroversion, orderliness, emotional stability, accommodation, and intellectual curiosity. Personality factors of patients from groups A and B were compared. History of present illness, clinical diagnosis, details of systemic ailment, and demographic information were collected.

RESULTS: Group A comprised HLA-B27-related uveitis (n = 30), uveitis due to sarcoidosis (n = 10), Vogt-Koyanagi-Harada syndrome (n = 5), sclero-kerato-uveitis due to rheumatoid arthritis (n = 5), and idiopathic uveitis in rest. Forty-five patients with uveitis had associated systemic ailment. Uveitis patients (n = 56) showed positive personality trait: S (social), C (calm), O (organized), A (accommodative), and I (inquisitive). In contrast, the control group (group B) which mainly comprised patients with non-pathological refractive error and visually insignificant cataract showed more number of negative personality traits (n = 62): R (reserved), L (limbic), U (unstructured), E (egocentric), and N (non-curious). This difference between the uveitis and control group was found to be statistically significant (p ≤ 0.001). The difference was also statistically significant for O (p = 0.008), U (p = 0.004), and C (p = 0.022) with chi-square test. Calm personality was found to be significantly associated with HLA-B27-related uveitis (p = 0.002). N, S, and A traits were seen almost equal in numbers in both the groups. U trait was absent in group A, whereas I trait had negligible presence in group B.

CONCLUSIONS: Our finding of an association between organized personality type and uveitis and calm personality and HLA-B27-related uveitis warrants further studies to understand the complex mechanism of psycho-immunology in uveitis.

Keywords: Behavior; Immune disease; Personality; Uveitis

References

  1. J Clin Rheumatol. 2010 Oct;16(7):313-6 - PubMed
  2. J Ocul Biol Dis Infor. 2009 Jun;2(2):84-93 - PubMed
  3. Ann Behav Med. 2000 Summer;22(3):180-90 - PubMed
  4. J Clin Rheumatol. 2011 Dec;17(8):424-8 - PubMed
  5. Health Psychol. 2001 Jan;20(1):4-11 - PubMed
  6. J Glaucoma. 2007 Dec;16(8):649-54 - PubMed
  7. Trans Am Ophthalmol Soc. 1986;84:799-845 - PubMed
  8. Insight. 2012 Spring;37(2):11-6 - PubMed
  9. Pain. 2001 Jan;89(2-3):275-83 - PubMed
  10. Psychol Sci. 2003 Sep;14(5):389-95 - PubMed
  11. J Pers Soc Psychol. 1987 Jan;52(1):81-90 - PubMed
  12. Brain Behav Immun. 2014 Jan;35:169-75 - PubMed
  13. Psychoneuroendocrinology. 2015 Feb;52:72-82 - PubMed
  14. Heart. 2007 Jul;93(7):783-4 - PubMed
  15. Rheumatology (Oxford). 2006 Oct;45(10):1288-93 - PubMed

Publication Types