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Forensic Toxicol. 2016;34:286-303. doi: 10.1007/s11419-016-0316-y. Epub 2016 Apr 27.

The 2-alkyl-2.

Forensic toxicology

Mitchell Longworth, Samuel D Banister, James B C Mack, Michelle Glass, Mark Connor, Michael Kassiou

Affiliations

  1. School of Chemistry, The University of Sydney, Sydney, NSW 2006 Australia.
  2. Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA USA.
  3. Department of Chemistry, Stanford University, Stanford, CA USA.
  4. School of Medical Sciences, The University of Auckland, Auckland, New Zealand.
  5. Department of Biomedical Sciences, Macquarie University, Sydney, Australia.
  6. Faculty of Health Sciences, The University of Sydney, Sydney, Australia.

PMID: 27547266 PMCID: PMC4971050 DOI: 10.1007/s11419-016-0316-y

Abstract

Indazole-derived synthetic cannabinoids (SCs) featuring an alkyl substituent at the 1-position and l-valinamide at the 3-carboxamide position (e.g., AB-CHMINACA) have been identified by forensic chemists around the world, and are associated with serious adverse health effects. Regioisomerism is possible for indazole SCs, with the 2-alkyl-2

Keywords: 2H-indazole regioisomer; CHMINACA; FUBINACA; Indazole synthetic cannabinoid; Manufacturing impurity with cannabinoid activity; PINACA

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