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Millan M, Delgado A, Caicedo LA, et al. Liver Angiosarcoma: Rare tumour associated with a poor prognosis, literature review and case report. Int J Surg Case Rep. 2016;28:165-168doi: 10.1016/j.ijscr.2016.09.044.
Millan, M., Delgado, A., Caicedo, L. A., Arrunategui, A. M., Meneses, C. A., Villegas, J. I., Serrano, O., Caicedo, L., Duque, M., & Echeverri, G. J. (2016). Liver Angiosarcoma: Rare tumour associated with a poor prognosis, literature review and case report. International journal of surgery case reports, 28165-168. https://doi.org/10.1016/j.ijscr.2016.09.044
Millan, Mauricio, et al. "Liver Angiosarcoma: Rare tumour associated with a poor prognosis, literature review and case report." International journal of surgery case reports vol. 28 (2016): 165-168. doi: https://doi.org/10.1016/j.ijscr.2016.09.044
Millan M, Delgado A, Caicedo LA, Arrunategui AM, Meneses CA, Villegas JI, Serrano O, Caicedo L, Duque M, Echeverri GJ. Liver Angiosarcoma: Rare tumour associated with a poor prognosis, literature review and case report. Int J Surg Case Rep. 2016;28:165-168. doi: 10.1016/j.ijscr.2016.09.044. Epub 2016 Sep 29. PMID: 27718433; PMCID: PMC5061303.
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Int J Surg Case Rep. 2016;28:165-168. doi: 10.1016/j.ijscr.2016.09.044. Epub 2016 Sep 29.

Liver Angiosarcoma: Rare tumour associated with a poor prognosis, literature review and case report.

International journal of surgery case reports

Mauricio Millan, Alejandro Delgado, Luis A Caicedo, Ana M Arrunategui, Carlos A Meneses, Jorge I Villegas, Oscar Serrano, Liliana Caicedo, Mauricio Duque, Gabriel J Echeverri

Affiliations

  1. Transplant Surgery Department, Fundación Valle de Lilí, Cali, Colombia; Centro para la Investigación en Cirugía Avanzada y Trasplantes, Universidad ICESI, Cali, Colombia.
  2. Centro de Investigaciones Clínicas, Fundación Valle del Lilí, Cali, Colombia; Centro para la Investigación en Cirugía Avanzada y Trasplantes, Universidad ICESI, Cali, Colombia.
  3. Pathology Department, Fundación Valle de Lilí, Cali, Colombia.
  4. Radiology Department, Fundación Valle de Lilí, Cali, Colombia.
  5. Transplant Surgery Department, Fundación Valle de Lilí, Cali, Colombia; Centro para la Investigación en Cirugía Avanzada y Trasplantes, Universidad ICESI, Cali, Colombia. Electronic address: [email protected].

PMID: 27718433 PMCID: PMC5061303 DOI: 10.1016/j.ijscr.2016.09.044

Abstract

INTRODUCTION: Liver angiosarcoma is a very uncommon tumour of mesenchymal origin, representing between 0.1-2% of all primary tumours of the liver, affecting mainly men in their sixth or seventh decade of life, with a high mortality in the first years (Chaudhary et al., 2015). Literature reports of its surgical treatment vary from a total or partial hepatectomy with or without liver transplant.

PRESENTATION OF CASE: A 37year old male, with a 7year history of a fatty liver, was found to have a 12cm diameter tumour in a cirrhotic liver, during an abdominal Computed Tomography (CT) scan. Patient was asymptomatic with negative tumour markers, yet tumour liver biopsy revealed a Liver Angiosarcoma with positive immunohistochemistry for neoplastic cells CD31 and CD34. Patient was deemed candidate for a partial hepatectomy of the affected liver segments which was done without complications and no evidence of other tumour lesions was found during surgery. Patient continued oncologic management with ongoing chemotherapy.

DISCUSION: Liver Angiosarcoma, although rare, persists with a high mortality due to its aggressive nature. Never the less liver transplantation, although proven to be an effective treatment for many pathologies that culminate in liver failure, fails to improve patients' survival and prognosis, when compared to partial hepatectomy as surgical management to for liver Angiosarcoma, CONCLUSION: Partial hepatectomy as surgical management, followed by adjuvant therapy, for Liver Angiosarcoma continues to prove favourable results and prognosis compared to Liver Transplantation.

Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

Keywords: Case Report,Case report,; Cirrhosis; Hepatectomy; Liver angiosarcoma; Liver transplant; Primary tumour

References

  1. Pediatr Transplant. 2014 Jun;18(4):E114-9 - PubMed
  2. Am J Transplant. 2006 Feb;6(2):392-7 - PubMed
  3. Medicine (Baltimore). 2015 May;94(19):e816 - PubMed
  4. Arch Pathol Lab Med. 1985 Sep;109(9):853-7 - PubMed
  5. World J Gastroenterol. 2015 May 21;21(19):6088-96 - PubMed
  6. Dig Dis Sci. 2003 Apr;48(4):677-82 - PubMed
  7. World J Surg Oncol. 2008 Sep 30;6:104 - PubMed
  8. Transplantation. 2013 Mar 27;95(6):872-7 - PubMed
  9. Lancet. 1979 Nov 24;2(8152):1120-3 - PubMed
  10. Hepatogastroenterology. 1990 Apr;37(2):188-93 - PubMed
  11. Int J Surg Case Rep. 2015;16:52-5 - PubMed
  12. Occup Environ Med. 1997 Jan;54(1):14-8 - PubMed
  13. Eur J Surg Oncol. 2015 Sep;41(9):1137-43 - PubMed

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