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J Renal Inj Prev. 2016 Aug 03;5(4):203-6. doi: 10.15171/jrip.2016.43. eCollection 2016.

Acute kidney injury in patients with paraquat intoxication; a case report and review of the literature.

Journal of renal injury prevention

Afshin Safaei Asl, Peyman Dadashzadeh

Affiliations

  1. Division of Nephrology, Department of Pediatrics, Guilan University of Medical Sciences, Rasht, Iran.
  2. Resident of Pediatrics , Guilan University of Medical Sciences, Rasht, Iran.

PMID: 27689124 PMCID: PMC5039990 DOI: 10.15171/jrip.2016.43

Abstract

Paraquat and diquat are classified as bipyridyl compounds not only leads to acute organ damage, but also to a variety of complications. Patients with severe paraquat-induced poisoning may succumb to multiple organ failure involving the circulatory and respiratory systems. Deliberate self-poisoning with paraquat continues to be a major public health concern in many developing countries. At present there is no specific antidote to paraquat poisoning, hence the need to more focus on prevention and in cases of poisoning aggressive decontamination to prevent further absorption. This article presented a 12-year-old male with acute kidney injury following the ingestion of paraquat in suicidal attempt and serves to explore the complications associated with paraquat poisoning and current recommended treatment.

Keywords: Acute kidney injury; Paraquat; Poisoning; Suicide

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