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Obata A, Kamei S, Okauchi S, et al. Strawberry milk-like blood in a subject with diabetic lipemia: dramatic change to transparent color after insulin therapy. Springerplus. 2016;5(1):1499doi: 10.1186/s40064-016-3202-5.
Obata, A., Kamei, S., Okauchi, S., Kimura, T., Hirukawa, H., Tanabe, A., Kinoshita, T., Kohara, K., Tatsumi, F., Shimoda, M., Nakanishi, S., Mune, T., Kaku, K., & Kaneto, H. (2016). Strawberry milk-like blood in a subject with diabetic lipemia: dramatic change to transparent color after insulin therapy. SpringerPlus, 5(1), 1499. https://doi.org/10.1186/s40064-016-3202-5
Obata, Atsushi, et al. "Strawberry milk-like blood in a subject with diabetic lipemia: dramatic change to transparent color after insulin therapy." SpringerPlus vol. 5,1 (2016): 1499. doi: https://doi.org/10.1186/s40064-016-3202-5
Obata A, Kamei S, Okauchi S, Kimura T, Hirukawa H, Tanabe A, Kinoshita T, Kohara K, Tatsumi F, Shimoda M, Nakanishi S, Mune T, Kaku K, Kaneto H. Strawberry milk-like blood in a subject with diabetic lipemia: dramatic change to transparent color after insulin therapy. Springerplus. 2016 Sep 07;5(1):1499. doi: 10.1186/s40064-016-3202-5. eCollection 2016. PMID: 27652072; PMCID: PMC5014774.
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Springerplus. 2016 Sep 07;5(1):1499. doi: 10.1186/s40064-016-3202-5. eCollection 2016.

Strawberry milk-like blood in a subject with diabetic lipemia: dramatic change to transparent color after insulin therapy.

SpringerPlus

Atsushi Obata, Shinji Kamei, Seizo Okauchi, Tomohiko Kimura, Hidenori Hirukawa, Akihito Tanabe, Tomoe Kinoshita, Kenji Kohara, Fuminori Tatsumi, Masashi Shimoda, Shuhei Nakanishi, Tomoatsu Mune, Kohei Kaku, Hideaki Kaneto

Affiliations

  1. Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192 Japan.

PMID: 27652072 PMCID: PMC5014774 DOI: 10.1186/s40064-016-3202-5

Abstract

INTRODUCTION: It is known that chylomicronemia is caused by several pathologies and is classified as primary and secondary chylomicronemia. Since hypertriglycemia is associated with an increased risk of cardiovascular disease and severe pancreatitis, it is very important to make a proper diagnosis of the cause of hypertriglycemia.

CASE DESCRIPTION: We herein present the case of a 40-year-old male who developed severe hypertriglycemia accompanied with acute exacerbation of type 2 diabetes mellitus. On admission, his blood glucose level was 306 mg/dl and HbA1c was 12.5 %. Moreover, serum triglyceride level was elevated up to 5661 mg/dl. When blood was drawn, it presented strawberry milk-like color. After receiving insulin treatment, he obtained good glycemic control and the serum became back to normal transparent color.

DISCUSSION AND EVALUATION: Insulin resistance reduces triglyceride clearance and also increases triglyceride release from adipocyte. It is known that glucose toxicity and strong insulin resistance induce inactivation of LPL, which results in chylomicronemia.

CONCLUSION: This case report suggests that when serum triglyceride level is markedly elevated due to diabetic lipemia, it is extremely important to obtain good glycemic control.

Keywords: Chylomicronemia; Diabetic lipemia; Hypertriglycemia

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