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Plank-Bazinet JL, Mundell NA. The paradox of Foxd3: how does it function in pluripotency and differentiation of embryonic stem cells?. Stem Cell Investig. 2016;3:73doi: 10.21037/sci.2016.09.20.
Plank-Bazinet, J. L., & Mundell, N. A. (2016). The paradox of Foxd3: how does it function in pluripotency and differentiation of embryonic stem cells?. Stem cell investigation, 373. https://doi.org/10.21037/sci.2016.09.20
Plank-Bazinet, Jennifer L, and Mundell, Nathan A. "The paradox of Foxd3: how does it function in pluripotency and differentiation of embryonic stem cells?." Stem cell investigation vol. 3 (2016): 73. doi: https://doi.org/10.21037/sci.2016.09.20
Plank-Bazinet JL, Mundell NA. The paradox of Foxd3: how does it function in pluripotency and differentiation of embryonic stem cells?. Stem Cell Investig. 2016 Nov 04;3:73. doi: 10.21037/sci.2016.09.20. eCollection 2016. PMID: 27868055; PMCID: PMC5104585.
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Stem Cell Investig. 2016 Nov 04;3:73. doi: 10.21037/sci.2016.09.20. eCollection 2016.

The paradox of Foxd3: how does it function in pluripotency and differentiation of embryonic stem cells?.

Stem cell investigation

Jennifer L Plank-Bazinet, Nathan A Mundell

Affiliations

  1. Office of Research on Women's Health, National Institutes of Health, Bethesda, MD, USA.
  2. Department of Genetics, Harvard Medical School, Boston, MA, USA.

PMID: 27868055 PMCID: PMC5104585 DOI: 10.21037/sci.2016.09.20

Abstract

Uncommitted cells of the early mammalian embryo transition through distinct stages of pluripotency, including establishment of ground state "naïve" pluripotency in the early epiblast, transition to a post-implantation "primed" state, and subsequent lineage commitment of the gastrulating epiblast. Previous transcriptional profiling of

Keywords: Pluripotency; embryonic stem cell (ESC); epiblast; forkhead; pioneer factor

Conflict of interest statement

The authors have no conflicts of interest to declare.

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