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Maderal AD, Kirsner RS. Clinical and Economic Benefits of Autologous Epidermal Grafting. Cureus. 2016;8(11):e875doi: 10.7759/cureus.875.
Maderal, A. D., & Kirsner, R. S. (2016). Clinical and Economic Benefits of Autologous Epidermal Grafting. Cureus, 8(11), e875. https://doi.org/10.7759/cureus.875
Maderal, Andrea D, and Kirsner, Robert S. "Clinical and Economic Benefits of Autologous Epidermal Grafting." Cureus vol. 8,11 (2016): e875. doi: https://doi.org/10.7759/cureus.875
Maderal AD, Kirsner RS. Clinical and Economic Benefits of Autologous Epidermal Grafting. Cureus. 2016 Nov 11;8(11):e875. doi: 10.7759/cureus.875. PMID: 27994993; PMCID: PMC5154427.
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Cureus. 2016 Nov 11;8(11):e875. doi: 10.7759/cureus.875.

Clinical and Economic Benefits of Autologous Epidermal Grafting.

Cureus

Andrea D Maderal, Robert S Kirsner

Affiliations

  1. Department of Dermatology and Cutaneous Surgery, University of Miami, Miller School of Medicine.

PMID: 27994993 PMCID: PMC5154427 DOI: 10.7759/cureus.875

Abstract

Chronic wounds are an increasingly prevalent disease with a significant healthcare burden. These wounds often do not respond to standard of care therapy alone, requiring the use of adjuvant therapies. Epidermal grafting, previously utilized primarily for correction of leukoderma, is increasingly being recognized as a beneficial therapy for wounds, both acute and chronic. Epidermal grafting has been shown to be effective in the management of chronic wounds, with successful healing in refractory patients. It has not only been shown to be effective, but it is also associated with lower cost and morbidity than traditional skin grafting techniques as well as improved donor site healing. Through the use of a novel epidermal harvesting system, the CelluTome™ Epidermal Harvesting System (KCI, an Acelity company, San Antonio, TX), this treatment modality has become more standardized, reproducible, and easy to use as well as less time consuming, making its use in the clinical setting more convenient and beneficial. Epidermal grafting, therefore, represents a promising, efficacious, and cost-effective option for treatment of refractory non-healing wounds.

Keywords: chronic wounds; epidermal grafting; venous ulcers

Conflict of interest statement

The authors have declared financial relationships, which are detailed in the next section.

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