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Middle East J Dig Dis. 2016 Oct;8(4):327-330. doi: 10.15171/mejdd.2016.44.

Resolution of Bile Duct Adenoma over Follow-up Period; A Case Report.

Middle East journal of digestive diseases

Mitra Ahadi, Ahmad Khosravi Khorashad, Hassan Saadatnia, Hassan Vosoughinia, Behrooz Davachi, Mohammadreza Farzanehfar, Kamran Ghaffarzadehgan, Bahram Memar, Elham Mokhtari Amirmajdi

Affiliations

  1. Assistant Professor, Department of Internal Medicine, Gastroenterology and Hepatology, Mashhad University of Medical Sciences, Mashhad, Iran.
  2. Professor, Department of Internal Medicine, Gastroenterology and Hepatology, Mashhad University of Medical Sciences, Mashhad, Iran.
  3. Assistant Professor, Department of Radiology, Mashhad University of Medical Sciences, Mashhad, Iran.
  4. Pathologist, Razavi Hospital, Mashhad, Iran.
  5. Associate Professor, Department of Pathology, Mashhad University of Medical Sciences, Mashhad, Iran.
  6. Assistant Professor, Department of medical sciences, Mashhad Branch, Islamic Azad University, Mashhad, Iran.

PMID: 27957298 PMCID: PMC5145302 DOI: 10.15171/mejdd.2016.44

Abstract

Bile duct adenoma (BDA) is a rare neoplasm of bile ducts with various clinical manifestations and imaging appearances. A few cases of BDA and their predisposing factors have been described. We report a 35-year-old woman with right upper quadrant pain who consumed oral contraceptive pills. Ultrasound study revealed three hypoechoic subcapsular liver masses; two of them were hypodense in computed tomography. Fine needle biopsy of the largest mass showed bile duct adenoma. Liver masses disappeared after discontinuing the pills over a 2-year follow-up. BDAs can manifest in imaging. Although previous studies have not reported tumor resolution over a follow-up period, we suggest paying more attention to predisposing factors in order to give an opportunity for tumor resolution by risk factor elimination.

Keywords: Bile duct adenoma; Follow up; Liver biopsy; Liver mass; Oral contraceptives

References

  1. World J Clin Oncol. 2012 Apr 10;3(4):63-6 - PubMed
  2. Am J Surg Pathol. 2001 Jul;25(7):956-60 - PubMed
  3. Case Rep Pathol. 2014;2014:874826 - PubMed
  4. Korean J Radiol. 2010 Sep-Oct;11(5):560-5 - PubMed
  5. World J Surg Oncol. 2014 Apr 26;12:125 - PubMed
  6. J Comput Assist Tomogr. 1999 Sep-Oct;23 (5):690-5 - PubMed
  7. Arch Surg. 1978 Mar;113(3):272-4 - PubMed

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