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Oman Med J. 2017 Jan;32(1):15-19. doi: 10.5001/omj.2017.03.

Treatment of Vaginal Atrophy with Vaginal Estrogen Cream in Menopausal Indian Women.

Oman medical journal

Maitri Shah, Zalak Karena, Sangita V Patel, Niyati Parmar, Pawan K Singh, Atul Sharma

Affiliations

  1. Department of Obstetrics & Gynecology, Government Medical College, Baroda, Gujarat, India.
  2. Department of Community Medicine, Government Medical College, Baroda, Gujarat, India.
  3. Pfizer India Ltd. Patel Estate, Jogeshwari (East), Mumbai, India.

PMID: 28042397 PMCID: PMC5187400 DOI: 10.5001/omj.2017.03

Abstract

OBJECTIVES: To measure the effect of vaginal estrogen cream in the treatment of vaginal atrophy in menopausal Indian women.

METHODS: A total of 50 menopausal women aged between 40 and 80 years old with symptoms of vaginal atrophy were selected and treated with 0.5 g vaginal estrogen cream, twice weekly for 12 weeks. The women were followed-up monthly where symptom score, Genital Health Clinical Evaluation (GHCE) score, vaginal pH, and vaginal maturation index (VMI) were assessed and compared to baseline data. Any adverse events were recorded.

RESULTS: There was a significant improvement (

CONCLUSIONS: Vaginal estrogen cream causes symptomatic relief in women of menopausal age in India suffering from vaginal atrophy.

Keywords: Atrophy; Estrogens, Conjugated; Postmenopause; Vaginal Cream; Women

References

  1. JAMA. 1999 Feb 10;281(6):537-44 - PubMed
  2. Menopause. 2012 Mar;19(3):257-71 - PubMed
  3. Menopause. 2009 Jul-Aug;16(4):719-27 - PubMed
  4. Mayo Clin Proc. 2010 Jan;85(1):87-94 - PubMed
  5. J Sex Med. 2009 Aug;6(8):2133-42 - PubMed
  6. Maturitas. 2010 Nov;67(3):233-8 - PubMed
  7. Cochrane Database Syst Rev. 2006 Oct 18;(4):CD001500 - PubMed
  8. Int J Gen Med. 2013;6:153-8 - PubMed
  9. Menopause. 2007 May-Jun;14(3 Pt 1):355-69; quiz 370-1 - PubMed
  10. Climacteric. 2013 Apr;16(2):203-4 - PubMed
  11. BJU Int. 2008 Apr;101(8):1005-11 - PubMed
  12. Menopause. 2013 Sep;20(9):888-902; quiz 903-4 - PubMed
  13. Clin Med Insights Reprod Health. 2014 Jun 08;8:23-30 - PubMed
  14. Obstet Gynecol. 2008 Nov;112(5):1053-60 - PubMed

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