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Ghasemi M, Nabipour I, Omrani A, et al. Precision medicine and molecular imaging: new targeted approaches toward cancer therapeutic and diagnosis. Am J Nucl Med Mol Imaging. 2016;6(6):310-327
Ghasemi, M., Nabipour, I., Omrani, A., Alipour, Z., & Assadi, M. (2016). Precision medicine and molecular imaging: new targeted approaches toward cancer therapeutic and diagnosis. American journal of nuclear medicine and molecular imaging, 6(6), 310-327.
Ghasemi, Mojtaba, et al. "Precision medicine and molecular imaging: new targeted approaches toward cancer therapeutic and diagnosis." American journal of nuclear medicine and molecular imaging vol. 6,6 (2016): 310-327.
Ghasemi M, Nabipour I, Omrani A, Alipour Z, Assadi M. Precision medicine and molecular imaging: new targeted approaches toward cancer therapeutic and diagnosis. Am J Nucl Med Mol Imaging. 2016 Nov 30;6(6):310-327. eCollection 2016. PMID: 28078184; PMCID: PMC5218860.
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Am J Nucl Med Mol Imaging. 2016 Nov 30;6(6):310-327. eCollection 2016.

Precision medicine and molecular imaging: new targeted approaches toward cancer therapeutic and diagnosis.

American journal of nuclear medicine and molecular imaging

Mojtaba Ghasemi, Iraj Nabipour, Abdolmajid Omrani, Zeinab Alipour, Majid Assadi

Affiliations

  1. The Persian Gulf Tropical Medicine Research Center, Bushehr University of Medical SciencesBushehr, Iran; Young Researchers and Elite Club, Bushehr Branch, Islamic Azad UniversityBushehr, Iran.
  2. The Persian Gulf Tropical Medicine Research Center, Bushehr University of Medical SciencesBushehr, Iran; The Future Studies Group, Iranian Academy of Medical SciencesTehran, Iran.
  3. Division of clinical studies, The Persian Gulf Nuclear Medicine Research Center, Bushehr University of Medical Sciences Bushehr, Iran.
  4. The Persian Gulf Nuclear Medicine Research Center, Bushehr University of Medical SciencesBushehr, Iran; Department of Molecular Imaging and Radionuclide Therapy (MIRT), Bushehr Medical University Hospital, Bushehr University of Medical SciencesBushehr, Iran.

PMID: 28078184 PMCID: PMC5218860

Abstract

This paper presents a review of the importance and role of precision medicine and molecular imaging technologies in cancer diagnosis with therapeutics and diagnostics purposes. Precision medicine is progressively becoming a hot topic in all disciplines related to biomedical investigation and has the capacity to become the paradigm for clinical practice. The future of medicine lies in early diagnosis and individually appropriate treatments, a concept that has been named precision medicine, i.e. delivering the right treatment to the right patient at the right time. Molecular imaging is quickly being recognized as a tool with the potential to ameliorate every aspect of cancer treatment. On the other hand, emerging high-throughput technologies such as omics techniques and systems approaches have generated a paradigm shift for biological systems in advanced life science research. In this review, we describe the precision medicine, difference between precision medicine and personalized medicine, precision medicine initiative, systems biology/medicine approaches (such as genomics, radiogenomics, transcriptomics, proteomics, and metabolomics), P4 medicine, relationship between systems biology/medicine approaches and precision medicine, and molecular imaging modalities and their utility in cancer treatment and diagnosis. Accordingly, the precision medicine and molecular imaging will enable us to accelerate and improve cancer management in future medicine.

Keywords: P4 medicine; Precision medicine; cancer theranostics; metabolomics-based systems medicine; molecular imaging; precision medicine initiative; radio-omics; systems biology

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