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Park HO, Moon SH, Kim JW, et al. Successful Anticoagulation Therapy for Antiphospholipid Syndrome with Mobile Aortic Thrombi. Vasc Specialist Int. 2016;32(4):186-189doi: 10.5758/vsi.2016.32.4.186.
Park, H. O., Moon, S. H., Kim, J. W., Byun, J. H., Kim, S. H., Yang, J. H., Lee, C. E., & Kim, J. D. (2016). Successful Anticoagulation Therapy for Antiphospholipid Syndrome with Mobile Aortic Thrombi. Vascular specialist international, 32(4), 186-189. https://doi.org/10.5758/vsi.2016.32.4.186
Park, Hyun Oh, et al. "Successful Anticoagulation Therapy for Antiphospholipid Syndrome with Mobile Aortic Thrombi." Vascular specialist international vol. 32,4 (2016): 186-189. doi: https://doi.org/10.5758/vsi.2016.32.4.186
Park HO, Moon SH, Kim JW, Byun JH, Kim SH, Yang JH, Lee CE, Kim JD. Successful Anticoagulation Therapy for Antiphospholipid Syndrome with Mobile Aortic Thrombi. Vasc Specialist Int. 2016 Dec;32(4):186-189. doi: 10.5758/vsi.2016.32.4.186. Epub 2016 Dec 31. PMID: 28042559; PMCID: PMC5198766.
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Vasc Specialist Int. 2016 Dec;32(4):186-189. doi: 10.5758/vsi.2016.32.4.186. Epub 2016 Dec 31.

Successful Anticoagulation Therapy for Antiphospholipid Syndrome with Mobile Aortic Thrombi.

Vascular specialist international

Hyun Oh Park, Seong Ho Moon, Jong Woo Kim, Joung Hun Byun, Sung Hwan Kim, Jun Ho Yang, Chung-Eun Lee, Jong-Duk Kim

Affiliations

  1. Department of Thoracic and Cardiovascular Surgery, College of Medicine and Institute of Health Sciences, Gyeongsang National University Changwon Hospital, Changwon, Jinju, Korea.
  2. Department of Thoracic and Cardiovascular Surgery, College of Medicine and Institute of Health Sciences, Gyeongsang National University Hospital, Jinju, Korea.

PMID: 28042559 PMCID: PMC5198766 DOI: 10.5758/vsi.2016.32.4.186

Abstract

Hypercoagulable states have been associated with aortic thrombosis. Antiphospholipid syndrome (APS) is one of the commonest types of acquired thrombophilia. We report the case of successful anticoagulation management in an APS patient with mobile thrombi within the aorta. A 58-year-old male patient presented to the emergency department (ED) with right-sided hemiparesis. His first symptoms were noted approximately 12-16 hours before presentation to the ED. Magnetic resonance imaging of the brain showed acute embolic infarction of the left frontal and parietotemporal lobes. Transesophageal echocardiography (TEE) and computed tomography angiography (CTA) demonstrated mobile thrombi attached to the wall of the ascending aorta and aortic arch. The patient was diagnosed with APS based on positivity of anti-beta-2 glycoprotein 1 antibodies, and was initiated on anticoagulation therapy. Repeated TEE and CTA revealed complete resolution of the thrombi after 12 days of treatment; the patient was discharged well.

Keywords: Antiphospholipid syndrome; Aorta; Thrombosis

Conflict of interest statement

None.

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