Display options
Cite
Katheria AC, Brown MK, Rich W, et al. Providing a Placental Transfusion in Newborns Who Need Resuscitation. Front Pediatr. 2017;5:1doi: 10.3389/fped.2017.00001.
Katheria, A. C., Brown, M. K., Rich, W., & Arnell, K. (2017). Providing a Placental Transfusion in Newborns Who Need Resuscitation. Frontiers in pediatrics, 51. https://doi.org/10.3389/fped.2017.00001
Katheria, Anup C, et al. "Providing a Placental Transfusion in Newborns Who Need Resuscitation." Frontiers in pediatrics vol. 5 (2017): 1. doi: https://doi.org/10.3389/fped.2017.00001
Katheria AC, Brown MK, Rich W, Arnell K. Providing a Placental Transfusion in Newborns Who Need Resuscitation. Front Pediatr. 2017 Jan 25;5:1. doi: 10.3389/fped.2017.00001. eCollection 2017. PMID: 28180126; PMCID: PMC5263890.
Copy Download .nbib Format: NLM
Share it on

Front Pediatr. 2017 Jan 25;5:1. doi: 10.3389/fped.2017.00001. eCollection 2017.

Providing a Placental Transfusion in Newborns Who Need Resuscitation.

Frontiers in pediatrics

Anup C Katheria, Melissa K Brown, Wade Rich, Kathy Arnell

Affiliations

  1. Neonatal Research Institute at Sharp Mary Birch Hospital for Women and Newborns , San Diego, CA , USA.

PMID: 28180126 PMCID: PMC5263890 DOI: 10.3389/fped.2017.00001

Abstract

Over the past decade, there have been several studies and reviews on the importance of providing a placental transfusion to the newborn. Allowing a placental transfusion to occur by delaying the clamping of the umbilical cord is an extremely effective method of enhancing arterial oxygen content, increasing cardiac output, and improving oxygen delivery. However, premature and term newborns who require resuscitation have impaired transitional hemodynamics and may warrant different methods to actively provide a placental transfusion while still allowing for resuscitation. In this review, we will provide evidence for providing a placental transfusion in these circumstances and methods for implementation. Several factors including cord clamping time, uterine contractions, umbilical blood flow, respirations, and gravity play an important role in determining placental transfusion volumes. Finally, while many practitioners agree that a placental transfusion is beneficial, it is not always straightforward to implement and can be performed using different methods, making this basic procedure important to discuss. We will review three placental transfusion techniques: delayed cord clamping, intact umbilical cord milking, and cut-umbilical cord milking. We will also review resuscitation with an intact cord and the evidence in term and preterm newborns supporting this practice. We will discuss perceived risks versus benefits of these procedures. Finally, we will provide key straightforward concepts and implementation strategies to ensure that placental-to-newborn transfusion can become routine practice at any institution.

Keywords: blood volume; cord milking; delayed cord clamping; hypovolemia; neonatal transition; perfusion; placental transfusion; resuscitation

References

  1. J Physiol. 2013 Apr 15;591(8):2113-26 - PubMed
  2. Circulation. 2015 Oct 20;132(16 Suppl 1):S204-41 - PubMed
  3. BMJ Open. 2015 Sep 30;5(9):e008494 - PubMed
  4. Pediatrics. 2015 Jul;136(1):61-9 - PubMed
  5. Circulation. 2015 Nov 3;132(18 Suppl 2):S543-60 - PubMed
  6. BMJ. 2011 Nov 15;343:d7157 - PubMed
  7. Cad Saude Publica. 2008;24 Suppl 2:S323-31 - PubMed
  8. J Perinatol. 2011 Apr;31 Suppl 1:S68-71 - PubMed
  9. Pediatrics. 2007 Mar;119(3):455-9 - PubMed
  10. Trop Med Int Health. 2007 May;12(5):603-16 - PubMed
  11. Trop Doct. 2004 Oct;34(4):218-22 - PubMed
  12. Eur J Pediatr. 2000 Oct;159(10):775-7 - PubMed
  13. PLoS One. 2015 Feb 17;10(2):e0117504 - PubMed
  14. Cochrane Database Syst Rev. 2013 Jul 11;(7):CD004074 - PubMed
  15. Early Hum Dev. 2015 Jul;91(7):407-11 - PubMed
  16. Arch Dis Child Fetal Neonatal Ed. 2012 Nov;97(6):F439-43 - PubMed
  17. BMJ. 1993 Jan 16;306(6871):172-5 - PubMed
  18. Indian Pediatr. 1997 Feb;34(2):103-6 - PubMed
  19. Resuscitation. 2015 Oct;95:202-22 - PubMed
  20. Med Hypotheses. 2009 Apr;72(4):458-63 - PubMed
  21. Lancet. 2014 Jul 19;384(9939):235-40 - PubMed
  22. Acta Paediatr. 1958 Sep;47(5):484-500 - PubMed
  23. Midwifery. 2016 Mar;34:42-6 - PubMed
  24. J Obstet Gynaecol Res. 2015 Jun;41(6):890-5 - PubMed
  25. Pediatr Res. 2015 May;77(5):608-14 - PubMed
  26. Lancet. 1969 Sep 6;2(7619):505-8 - PubMed
  27. J Perinatol. 2000 Sep;20(6):351-4 - PubMed
  28. Pediatrics. 2014 Aug;134(2):265-72 - PubMed
  29. J Pediatr. 2014 May;164(5):1045-1050.e1 - PubMed
  30. Indian J Pediatr. 2015 Oct;82(10 ):890-5 - PubMed
  31. J Pediatr. 2016 Jan;168:50-5.e1 - PubMed
  32. BMC Pediatr. 2014 May 29;14 :135 - PubMed
  33. Int J Gynaecol Obstet. 2009 Oct;107 Suppl 1:S47-62, S63-4 - PubMed
  34. J Pediatr. 2016 Nov;178:75-80.e3 - PubMed
  35. J Midwifery Womens Health. 2014 Nov-Dec;59(6):635-44 - PubMed
  36. Pediatrics. 2006 Jan;117(1):93-8 - PubMed
  37. Am J Obstet Gynecol. 2013 Feb;208(2):120.e1-6 - PubMed
  38. Matern Health Neonatol Perinatol. 2015 May 22;1:15 - PubMed
  39. J Perinat Neonatal Nurs. 2012 Jul-Sep;26(3):202-17; quiz 218-9 - PubMed
  40. Transfusion. 2003 Aug;43(8):1168-72 - PubMed
  41. Early Hum Dev. 1997 Oct 10;49(3):193-202 - PubMed
  42. Obstet Gynecol. 2011 Feb;117(2 Pt 1):205-11 - PubMed
  43. Arch Argent Pediatr. 2010 Jun;108(3):201-8 - PubMed
  44. J Perinatol. 2003 Sep;23(6):466-72 - PubMed
  45. J Pediatr. 1997 Feb;130(2):225-30 - PubMed
  46. Am J Obstet Gynecol. 2015 Mar;212(3):394.e1-5 - PubMed
  47. J Paediatr Child Health. 1997 Aug;33(4):308-10 - PubMed
  48. Cochrane Database Syst Rev. 2004 Oct 18;(4):CD003248 - PubMed
  49. Online J Curr Clin Trials. 1993 Dec 29;Doc No 110:[2002 words; 26 paragraphs] - PubMed
  50. Pediatrics. 2006 Apr;117(4):1235-42 - PubMed
  51. PLoS One. 2014 Apr 07;9(4):e94085 - PubMed
  52. Lancet. 1969 Oct 25;2(7626):871-3 - PubMed
  53. S Afr Med J. 1988 Jan 23;73(2):104-6 - PubMed
  54. N Engl J Med. 1954 Apr 15;250(15):629-32 - PubMed
  55. Obstet Gynecol. 2012 Dec;120(6):1522-6 - PubMed
  56. Cochrane Database Syst Rev. 2012 Aug 15;(8):CD003248 - PubMed
  57. Am J Obstet Gynecol. 1962 Jul 1;84:1-12 - PubMed
  58. Br Heart J. 1969 Jan;31(1):122-6 - PubMed
  59. J Perinatol. 2012 Aug;32(8):580-4 - PubMed
  60. Lancet. 2006 Jun 17;367(9527):1997-2004 - PubMed
  61. Matern Health Neonatol Perinatol. 2016 Jun 30;2:5 - PubMed

Publication Types