Open Orthop J. 2016 Nov 30;10:669-678. doi: 10.2174/1874325001610010669. eCollection 2016.
Aggressive Early Debridement in Treatment of Acute Periprosthetic Joint Infections After Hip and Knee Replacements.
The open orthopaedics journal
Andrea Volpin, Mohamed Sukeik, Sulaiman Alazzawi, Fares Sami Haddad
Affiliations
Affiliations
- Department of Trauma and Orthopaedics, University College London Hospital, 235 Euston Road, NW1 2BU, London, United Kingdom.
- Department of Trauma and Orthopaedics, The Royal London Hospital, Whitechapel, E1 1BB, London, United Kingdom.
PMID: 28144377
PMCID: PMC5220182 DOI: 10.2174/1874325001610010669
Abstract
BACKGROUND: Periprosthetic Joint Infection Remains a Dreaded Complication After Hip and Knee Replacement Surgery. Treatment Options for Acute Postoperative and Acute Hematogenous Infections Include Arthroscopic or Open Debridement With Retention or Exchange of the Prostheses. This Review Article Aims to Summarize the Evidence for Management of Acute Postoperative And Acute Hematogenous Infections.
METHODS: A Systematic Literature Search Was Performed Using a Computer-based Search Engine Covering Medline (OvidSP), PubMed Database (U.S. National Library of Medicine, National Institutes of Health), Embase, Web of Science, Cochrane and Google Scholar for Relevant Articles.
RESULTS: Common Themes Around Treatment of Acute Postoperative and Acute Hematogenous Infections Discussed in this Review Include the Timing of Intervention, Description of the Optimal Procedure and How we Perform it at our Institution, the Role of Arthroscopic Debridement, Most Commonly Isolated Micro-organisms and Prognostic Factors for Infection Control.
CONCLUSION: Success in Treating Acute Postoperative and Acute Hematogenous Infections Depends on Early Diagnosis and Aggressive Surgical Debridement Combined With Effective Antibiotic Therapy.
Keywords: Acute; Arthroplasty; Debridement; Hip; Irrigation; Knee; Periprosthetic joint infection
References
- J Clin Microbiol. 2012 Nov;50(11):3501-8 - PubMed
- Clin Infect Dis. 2008 Dec 1;47(11):1403-9 - PubMed
- J Arthroplasty. 2009 Sep;24(6 Suppl):101-4 - PubMed
- J Arthroplasty. 1998 Jan;13(1):22-8 - PubMed
- Int Orthop. 2005 Apr;29(2):113-6 - PubMed
- Int Orthop. 2013 Aug;37(8):1471-5 - PubMed
- J Bone Joint Surg Am. 2006 Dec;88 Suppl 4:138-47 - PubMed
- Clin Orthop Relat Res. 2003 Nov;(416):129-34 - PubMed
- Orthop Clin North Am. 1975 Oct;6(4):991-1003 - PubMed
- World J Orthop. 2014 Nov 18;5(5):667-76 - PubMed
- Hip Int. 2012 Jul-Aug;22 Suppl 8:S19-24 - PubMed
- Clin Orthop Relat Res. 2011 Apr;469(4):970-6 - PubMed
- J Arthroplasty. 2014 Mar;29(3):465-8 - PubMed
- Clin Infect Dis. 1997 May;24(5):914-9 - PubMed
- Eur J Clin Microbiol Infect Dis. 2012 Dec;31(12):3367-74 - PubMed
- Arch Orthop Trauma Surg. 2011 Sep;131(9):1233-8 - PubMed
- J Med Microbiol. 2012 Mar;61(Pt 3):309-16 - PubMed
- Arthroscopy. 2014 May;30(5):599-606 - PubMed
- Acta Orthop. 2014 Aug;85(4):383-8 - PubMed
- Clin Orthop Relat Res. 2010 Sep;468(9):2392-6 - PubMed
- Infect Dis Ther. 2014 Dec;3(2):235-43 - PubMed
- J Arthroplasty. 2011 Sep;26(6 Suppl):109-13 - PubMed
- Intern Med J. 2013 Jul;43(7):810-5 - PubMed
- Knee Surg Sports Traumatol Arthrosc. 2012 Dec;20(12):2445-53 - PubMed
- Clin Infect Dis. 2003 Apr 1;36(7):845-9 - PubMed
- Knee Surg Sports Traumatol Arthrosc. 2016 Jan;24(1):287-94 - PubMed
- J Arthroplasty. 2010 Oct;25(7):1022-7 - PubMed
- J Clin Microbiol. 1998 Oct;36(10):2932-9 - PubMed
- Clin Microbiol Infect. 2007 Jun;13(6):586-91 - PubMed
- Clin Orthop Relat Res. 2007 Aug;461:44-7 - PubMed
- Ann Med. 2009;41(2):109-19 - PubMed
- Infection. 2014 Jun;42(3):511-9 - PubMed
- J Antimicrob Chemother. 2009 Jun;63(6):1264-71 - PubMed
- Clin Orthop Relat Res. 2011 Jan;469(1):18-25 - PubMed
- Clin Orthop Relat Res. 2009 Jan;467(1):174-80 - PubMed
- J Arthroplasty. 2000 Jun;15(4):430-6 - PubMed
- Int J Med Sci. 2009 Sep 02;6(5):241-6 - PubMed
- Clin Orthop Relat Res. 2002 Nov;(404):125-31 - PubMed
- Int J Antimicrob Agents. 2010 Apr;35(4):322-32 - PubMed
- Surg Clin North Am. 2014 Dec;94(6):1265-81 - PubMed
- J Arthroplasty. 1999 Dec;14(8):903-10 - PubMed
- J Arthroplasty. 2014 Mar;29(3):469-72 - PubMed
- Clin Orthop Relat Res. 2005 Oct;439:27-31 - PubMed
- Clin Infect Dis. 2006 Feb 15;42(4):471-8 - PubMed
- Clin Infect Dis. 2013 Jan;56(2):182-94 - PubMed
- Interdiscip Perspect Infect Dis. 2013;2013:542796 - PubMed
- J Bone Joint Surg Am. 1998 Sep;80(9):1306-13 - PubMed
- J Bone Joint Surg Br. 2004 Jan;86(1):39-42 - PubMed
- N Engl J Med. 2004 Oct 14;351(16):1645-54 - PubMed
- Antimicrob Agents Chemother. 2013 Jan;57(1):350-5 - PubMed
- Clin Orthop Relat Res. 2011 Nov;469(11):3043-8 - PubMed
- Arthroscopy. 1988;4(3):182-6 - PubMed
- Acta Orthop. 2013 Aug;84(4):380-6 - PubMed
- Ann R Coll Surg Engl. 2004 Jul;86(4):267-71 - PubMed
- JAMA. 1998 May 20;279(19):1537-41 - PubMed
- Clin Orthop Relat Res. 2010 Aug;468(8):2024-8 - PubMed
- Orthopedics. 2008 Jun;31(6):581-8; quiz 589-90 - PubMed
- Clin Orthop Relat Res. 1991 Dec;(273):105-12 - PubMed
- World J Orthop. 2014 Jul 18;5(3):218-24 - PubMed
- Clin Microbiol Infect. 2011 Jun;17(6):862-7 - PubMed
- Acta Orthop. 2012 Jun;83(3):227-32 - PubMed
- J Bone Joint Surg Am. 1996 Apr;78(4):512-23 - PubMed
- Int J Med Sci. 2009 Sep 04;6(5):287-95 - PubMed
- FEMS Immunol Med Microbiol. 2012 Jul;65(2):158-68 - PubMed
- J Bone Joint Surg Br. 2008 Feb;90(2):145-8 - PubMed
- Knee Surg Relat Res. 2013 Dec;25(4):155-64 - PubMed
- Clin Infect Dis. 2013 Jan;56(1):1-10 - PubMed
- Acta Orthop. 2007 Dec;78(6):755-65 - PubMed
- Am J Med. 2006 Nov;119(11):993.e7-10 - PubMed
- Clin Orthop Relat Res. 1988 Apr;(229):131-42 - PubMed
- Clin Orthop Relat Res. 2012 Nov;470(11):3164-70 - PubMed
- Int Orthop. 2015 Mar;39(3):397-401 - PubMed
- J Arthroplasty. 1997 Jun;12 (4):426-33 - PubMed
- J Bone Joint Surg Br. 2006 Feb;88(2):149-55 - PubMed
Publication Types