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Open Orthop J. 2016 Nov 30;10:669-678. doi: 10.2174/1874325001610010669. eCollection 2016.

Aggressive Early Debridement in Treatment of Acute Periprosthetic Joint Infections After Hip and Knee Replacements.

The open orthopaedics journal

Andrea Volpin, Mohamed Sukeik, Sulaiman Alazzawi, Fares Sami Haddad

Affiliations

  1. Department of Trauma and Orthopaedics, University College London Hospital, 235 Euston Road, NW1 2BU, London, United Kingdom.
  2. Department of Trauma and Orthopaedics, The Royal London Hospital, Whitechapel, E1 1BB, London, United Kingdom.

PMID: 28144377 PMCID: PMC5220182 DOI: 10.2174/1874325001610010669

Abstract

BACKGROUND: Periprosthetic Joint Infection Remains a Dreaded Complication After Hip and Knee Replacement Surgery. Treatment Options for Acute Postoperative and Acute Hematogenous Infections Include Arthroscopic or Open Debridement With Retention or Exchange of the Prostheses. This Review Article Aims to Summarize the Evidence for Management of Acute Postoperative And Acute Hematogenous Infections.

METHODS: A Systematic Literature Search Was Performed Using a Computer-based Search Engine Covering Medline (OvidSP), PubMed Database (U.S. National Library of Medicine, National Institutes of Health), Embase, Web of Science, Cochrane and Google Scholar for Relevant Articles.

RESULTS: Common Themes Around Treatment of Acute Postoperative and Acute Hematogenous Infections Discussed in this Review Include the Timing of Intervention, Description of the Optimal Procedure and How we Perform it at our Institution, the Role of Arthroscopic Debridement, Most Commonly Isolated Micro-organisms and Prognostic Factors for Infection Control.

CONCLUSION: Success in Treating Acute Postoperative and Acute Hematogenous Infections Depends on Early Diagnosis and Aggressive Surgical Debridement Combined With Effective Antibiotic Therapy.

Keywords: Acute; Arthroplasty; Debridement; Hip; Irrigation; Knee; Periprosthetic joint infection

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