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Mumtaz K, Metwally S, Modi RM, et al. Impact of transjugular intrahepatic porto-systemic shunt on post liver transplantation outcomes: Study based on the United Network for Organ Sharing database. World J Hepatol. 2017;9(2):99-105doi: 10.4254/wjh.v9.i2.99.
Mumtaz, K., Metwally, S., Modi, R. M., Patel, N., Tumin, D., Michaels, A. J., Hanje, J., El-Hinnawi, A., Hayes, D., & Black, S. M. (2017). Impact of transjugular intrahepatic porto-systemic shunt on post liver transplantation outcomes: Study based on the United Network for Organ Sharing database. World journal of hepatology, 9(2), 99-105. https://doi.org/10.4254/wjh.v9.i2.99
Mumtaz, Khalid, et al. "Impact of transjugular intrahepatic porto-systemic shunt on post liver transplantation outcomes: Study based on the United Network for Organ Sharing database." World journal of hepatology vol. 9,2 (2017): 99-105. doi: https://doi.org/10.4254/wjh.v9.i2.99
Mumtaz K, Metwally S, Modi RM, Patel N, Tumin D, Michaels AJ, Hanje J, El-Hinnawi A, Hayes D, Black SM. Impact of transjugular intrahepatic porto-systemic shunt on post liver transplantation outcomes: Study based on the United Network for Organ Sharing database. World J Hepatol. 2017 Jan 18;9(2):99-105. doi: 10.4254/wjh.v9.i2.99. PMID: 28144391; PMCID: PMC5241534.
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World J Hepatol. 2017 Jan 18;9(2):99-105. doi: 10.4254/wjh.v9.i2.99.

Impact of transjugular intrahepatic porto-systemic shunt on post liver transplantation outcomes: Study based on the United Network for Organ Sharing database.

World journal of hepatology

Khalid Mumtaz, Sherif Metwally, Rohan M Modi, Nishi Patel, Dmitry Tumin, Anthony J Michaels, James Hanje, Ashraf El-Hinnawi, Don Hayes, Sylvester M Black

Affiliations

  1. Khalid Mumtaz, Anthony J Michaels, James Hanje, Wexner Medical Center, Gastroenterology, Hepatology and Nutrition Division, the Ohio State University, Columbus, OH 43210, United States.

PMID: 28144391 PMCID: PMC5241534 DOI: 10.4254/wjh.v9.i2.99

Abstract

AIM: To determine the impact of transjugular intrahepatic porto-systemic shunt (TIPS) on post liver transplantation (LT) outcomes.

METHODS: Utilizing the United Network for Organ Sharing (UNOS) database, we compared patients who underwent LT from 2002 to 2013 who had underwent TIPS to those without TIPS for the management of ascites while on the LT waitlist. The impact of TIPS on 30-d mortality, length of stay (LOS), and need for re-LT were studied. For evaluation of mean differences between baseline characteristics for patients with and without TIPS, we used unpaired

RESULTS: We included adult patients (age ≥ 18 years) who underwent LT from May 2002 to September 2013. Only those undergoing TIPS after listing and before liver transplant were included in the TIPS group. We excluded patients with variceal bleeding within two weeks of listing for LT and those listed for acute liver failure or hepatocellular carcinoma. Of 114770 LT in the UNOS database, 32783 (28.5%) met inclusion criteria. Of these 1366 (4.2%) had TIPS between the time of listing and LT. We found that TIPS increased the days on waitlist (408 ± 553 d) as compared to those without TIPS (183 ± 330 d),

CONCLUSION: TIPS did increase time on waitlist for LT. More importantly, TIPS was not associated with 30-d mortality and re-LT, but it did lengthen hospital LOS after transplantation.

Keywords: Ascites; Liver; Model for end-stage liver disease; Mortality; Shunt; Transjugular; Transjugular intrahepatic porto-systemic shunt; Transplantation

Conflict of interest statement

Conflict-of-interest statement: None of the authors have any conflicts of interest.

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