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Takahashi M, Hosomichi K, Yamaguchi T, et al. Whole-exome sequencing analysis of supernumerary teeth occurrence in Japanese individuals. Hum Genome Var. 2017;4:16046doi: 10.1038/hgv.2016.46.
Takahashi, M., Hosomichi, K., Yamaguchi, T., Yano, K., Funatsu, T., Adel, M., Haga, S., Maki, K., & Tajima, A. (2017). Whole-exome sequencing analysis of supernumerary teeth occurrence in Japanese individuals. Human genome variation, 416046. https://doi.org/10.1038/hgv.2016.46
Takahashi, Masahiro, et al. "Whole-exome sequencing analysis of supernumerary teeth occurrence in Japanese individuals." Human genome variation vol. 4 (2017): 16046. doi: https://doi.org/10.1038/hgv.2016.46
Takahashi M, Hosomichi K, Yamaguchi T, Yano K, Funatsu T, Adel M, Haga S, Maki K, Tajima A. Whole-exome sequencing analysis of supernumerary teeth occurrence in Japanese individuals. Hum Genome Var. 2017 Jan 26;4:16046. doi: 10.1038/hgv.2016.46. eCollection 2017. PMID: 28144447; PMCID: PMC5267165.
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Hum Genome Var. 2017 Jan 26;4:16046. doi: 10.1038/hgv.2016.46. eCollection 2017.

Whole-exome sequencing analysis of supernumerary teeth occurrence in Japanese individuals.

Human genome variation

Masahiro Takahashi, Kazuyoshi Hosomichi, Tetsutaro Yamaguchi, Keisuke Yano, Takahiro Funatsu, Mohamed Adel, Shugo Haga, Koutaro Maki, Atsushi Tajima

Affiliations

  1. Department of Orthodontics, School of Dentistry, Showa University , Tokyo, Japan.
  2. Department of Bioinformatics and Genomics, Graduate School of Advanced Preventive Medical Sciences, Kanazawa University , Ishikawa, Japan.
  3. Verde Orthodontic Dental Clinic , Tokyo, Japan.
  4. Division of Dentistry for Persons with Disabilities, Department of Special Needs Dentistry, School of Dentistry, Showa University , Tokyo, Japan.

PMID: 28144447 PMCID: PMC5267165 DOI: 10.1038/hgv.2016.46

Abstract

A common disorder of human dentition is the existence of supernumerary teeth. Impacted supernumerary teeth occur most frequently in the maxillary incisor area and are termed mesiodens. We conducted whole-exome sequencing of non-syndromic Japanese individuals possessing supernumerary teeth to identify genes and/or loci involved in the pathogenesis of the condition.

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