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McKibben RA, Al Rifai M, Mathews LM, et al. Primary Prevention of Atherosclerotic Cardiovascular Disease in Women. Curr Cardiovasc Risk Rep. 2015;10doi: 10.1007/s12170-015-0480-3.
McKibben, R. A., Al Rifai, M., Mathews, L. M., & Michos, E. D. (2016). Primary Prevention of Atherosclerotic Cardiovascular Disease in Women. Current cardiovascular risk reports, 10. https://doi.org/10.1007/s12170-015-0480-3
McKibben, Rebeccah A, et al. "Primary Prevention of Atherosclerotic Cardiovascular Disease in Women." Current cardiovascular risk reports vol. 10 (2016). doi: https://doi.org/10.1007/s12170-015-0480-3
McKibben RA, Al Rifai M, Mathews LM, Michos ED. Primary Prevention of Atherosclerotic Cardiovascular Disease in Women. Curr Cardiovasc Risk Rep. 2016 Jan;10. doi: 10.1007/s12170-015-0480-3. Epub 2015 Dec 29. PMID: 28149430; PMCID: PMC5279938.
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Curr Cardiovasc Risk Rep. 2016 Jan;10. doi: 10.1007/s12170-015-0480-3. Epub 2015 Dec 29.

Primary Prevention of Atherosclerotic Cardiovascular Disease in Women.

Current cardiovascular risk reports

Rebeccah A McKibben, Mahmoud Al Rifai, Lena M Mathews, Erin D Michos

Affiliations

  1. Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins University School of Medicine, Baltimore, MD, USA 21287.

PMID: 28149430 PMCID: PMC5279938 DOI: 10.1007/s12170-015-0480-3

Abstract

Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of morbidity and mortality among women. Despite improvements in cardiovascular disease prevention efforts, there remain gaps in cardiovascular disease awareness among women, as well as age and racial disparities in ASCVD outcomes for women. Disparity also exists in the impact the traditional risk factors confer on ASCVD risk between women and men, with smoking and diabetes both resulting in stronger relative risks in women compared to men. Additionally there are risk factors that are unique to women (such as pregnancy-related factors) or that disproportionally affect women (such as auto-immune disease) where preventive efforts should be targeted. Risk assessment and management must also be sex-specific to effectively reduce cardiovascular disease and improve outcomes among women. Evidence supports the use of statin therapy for primary prevention in women at higher ASCVD risk. However, some pause should be given to prescribing aspirin therapy in women without known ASCVD, with most evidence supporting the use of aspirin for women≥65 years not at increased risk for bleeding. This review article will summarize (1) traditional and non-traditional assessments of ASCVD risk and (2) lifestyle and pharmacologic therapies for the primary prevention of ASCVD in women.

Keywords: Cardiovascular Disease; Prevention; Risk; Women

Conflict of interest statement

Compliance with ethics guidelines Conflict of interest Rebeccah McKibben, Lena Mathews, Mahmoud Al Rifai and Erin Michos have no relevant disclosures to report.

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