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Numan O, Vural F, Aka N, et al. TORCH seroprevalence among patients attending Obstetric Care Clinic of Haydarpasa Training and Research Hospital affiliated to Association of Istanbul Northern Anatolia Public Hospitals. North Clin Istanb. 2015;2(3):203-209doi: 10.14744/nci.2015.55376.
Numan, O., Vural, F., Aka, N., Alpay, M., & Coskun, A. D. (2015). TORCH seroprevalence among patients attending Obstetric Care Clinic of Haydarpasa Training and Research Hospital affiliated to Association of Istanbul Northern Anatolia Public Hospitals. Northern clinics of Istanbul, 2(3), 203-209. https://doi.org/10.14744/nci.2015.55376
Numan, Onur, et al. "TORCH seroprevalence among patients attending Obstetric Care Clinic of Haydarpasa Training and Research Hospital affiliated to Association of Istanbul Northern Anatolia Public Hospitals." Northern clinics of Istanbul vol. 2,3 (2015): 203-209. doi: https://doi.org/10.14744/nci.2015.55376
Numan O, Vural F, Aka N, Alpay M, Coskun AD. TORCH seroprevalence among patients attending Obstetric Care Clinic of Haydarpasa Training and Research Hospital affiliated to Association of Istanbul Northern Anatolia Public Hospitals. North Clin Istanb. 2015 Dec 25;2(3):203-209. doi: 10.14744/nci.2015.55376. eCollection 2015. PMID: 28058368; PMCID: PMC5175107.
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North Clin Istanb. 2015 Dec 25;2(3):203-209. doi: 10.14744/nci.2015.55376. eCollection 2015.

TORCH seroprevalence among patients attending Obstetric Care Clinic of Haydarpasa Training and Research Hospital affiliated to Association of Istanbul Northern Anatolia Public Hospitals.

Northern clinics of Istanbul

Onur Numan, Fisun Vural, Nurettin Aka, Murat Alpay, Ayse Deniz Erturk Coskun

Affiliations

  1. Department of Obstetrics and Gynaecology, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey.

PMID: 28058368 PMCID: PMC5175107 DOI: 10.14744/nci.2015.55376

Abstract

OBJECTIVE: Toxoplasma gondii, Rubella, Cytomegalovirus and Herpes simplex viruses are microorganisms that cause congenital infections and they are called briefly as TORCH. There is an ongoing argument for the screening of reproductive age women due to the high cost of tests. For a test to be used in screening, prevalence of disease in this population should be known. The aim of this study was to investigate TORCH seroprevalence among women attending a teaching hospital in Istanbul.

METHODS: A total of 1101 patients attending outpatient clinic of Obstetric Care Clinic of Haydarpasa Training and Research Hospital affiliated to Association of Istanbul Northern Anatolia Public Hospitals between September 2013 to January 2015 and their laboratory data were evaluated retrospectively. We investigated Ig G and M seropositivity rates against TORCH.

RESULTS: The age of the patients ranged between 17-47 years with a mean age of 30.3±5.8 years. Pregnant population had 99.5% anti-CMV Ig G (+), 94.2% anti-Rubella Ig G (+), 31% anti-Toxoplasma Ig G (+). Seroprevalence for Anti IgM was 0.5% for CMV, 0.2% for rubella.

CONCLUSION: The screening for Toxoplasma gondii may be suggested since the prevalence is not high in our population. The screening of CMV is not meaningful, due to high seroprevalence. Although seroprevalence of rubella is also high, it may be suggested for preconception vaccination especially in women above 20 years of age born prior to National Vaccination Programme.

Keywords: CMV; TORCH; pregnancy; rubella; screening tests; toxoplasma

Conflict of interest statement

No conflict of interest was declared by the authors.

References

  1. BMJ. 2006 Jan 14;332(7533):76-80 - PubMed
  2. Eur J Obstet Gynecol Reprod Biol. 2004 May 10;114(1):3-11 - PubMed
  3. Scand J Infect Dis. 2007;39(3):231-4 - PubMed
  4. J Obstet Gynaecol Res. 2013 Mar;39(3):653-7 - PubMed
  5. Arch Gynecol Obstet. 2014 Dec;290(6):1115-20 - PubMed
  6. Prenat Diagn. 2005 Nov;25(11):1028-31 - PubMed
  7. Can Fam Physician. 2014 Apr;60(4):334-6 - PubMed
  8. Turkiye Parazitol Derg. 2007;31(3):176-9 - PubMed
  9. New Microbiol. 2008 Oct;31(4):451-5 - PubMed
  10. Clin Lab Med. 2010 Sep;30(3):709-20 - PubMed
  11. Clin Invest Med. 2009 Feb 01;32(1):E43-7 - PubMed
  12. Mikrobiyol Bul. 2012 Apr;46(2):290-4 - PubMed
  13. Rev Med Virol. 2007 Jul-Aug;17(4):253-76 - PubMed
  14. Clin Vaccine Immunol. 2011 Nov;18(11):1895-9 - PubMed
  15. Turkiye Parazitol Derg. 2015 Sep;39(3):200-4 - PubMed

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